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Nitrogen containing heterocycles as anticancer agents: A medicinal chemistry perspective
Cancer is one of the major healthcare challenges across the globe. Several anticancer
drugs are available on the market but they either lack specificity or have poor safety, severe …
drugs are available on the market but they either lack specificity or have poor safety, severe …
Prescribed drugs containing nitrogen heterocycles: an overview
Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …
A review on recent advances in nitrogen-containing molecules and their biological applications
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable
source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by …
source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by …
Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs–a review
Quinoline, which consists of benzene fused with N-heterocyclic pyridine, has received
considerable attention as a core template in drug design because of its broad spectrum of …
considerable attention as a core template in drug design because of its broad spectrum of …
[HTML][HTML] Novel pyridine and pyrimidine derivatives as promising anticancer agents: A review
Pyridines and pyrimidines are the class of heterocyclic nitrogenous compounds having
plethora of applications in anticancer drug development. These synthetic sources serve as …
plethora of applications in anticancer drug development. These synthetic sources serve as …
Bioactive pyrrole-based compounds with target selectivity
The discovery of novel synthetic compounds with drug-like properties is an ongoing
challenge in medicinal chemistry. Natural products have inspired the synthesis of …
challenge in medicinal chemistry. Natural products have inspired the synthesis of …
Natural source, bioactivity and synthesis of benzofuran derivatives
Y Miao, Y Hu, J Yang, T Liu, J Sun, X Wang - RSC advances, 2019 - pubs.rsc.org
Benzofuran compounds are a class of compounds that are ubiquitous in nature. Numerous
studies have shown that most benzofuran compounds have strong biological activities such …
studies have shown that most benzofuran compounds have strong biological activities such …
Pharmacological significance of nitrogen-containing five and six-membered heterocyclic scaffolds as potent cholinesterase inhibitors for drug discovery
N-heterocycles are crucial due to their biological, chemical, and practical significance. They
are heavily investigated in biological processes involving anticancer, anti-inflammatory …
are heavily investigated in biological processes involving anticancer, anti-inflammatory …
Hepatocellular carcinoma: etiology and current and future drugs
Hepatocellular carcinoma (HCC) is swiftly increasing in prevalence globally with a high
mortality rate. The progression of HCC in patients is induced with advanced fibrosis, mainly …
mortality rate. The progression of HCC in patients is induced with advanced fibrosis, mainly …
Comprehensive review on the Bis–heterocyclic compounds and their anticancer efficacy
Heterocyclic compounds are one of the largest family of organic compounds with broad
range of applications in medicinal chemistry and agrochemicals product. Bis-heterocycle …
range of applications in medicinal chemistry and agrochemicals product. Bis-heterocycle …