Newly hatched chickens are confronted by a wide array of pathogenic microbes because
their adaptive immune defences have limited capabilities to control these pathogens. In such …

NLRC5 is a member of the NLR family that acts as a transcriptional activator of MHC class I
genes. In line with the function of several related NLR proteins in innate immune responses …

Innate immunity activates the corresponding immune response relying on multiple pattern
recognition receptors (PRRs) that includes pattern recognition receptors (PRRs), like NOD …

Non-alcoholic steatohepatitis (NASH, also known as MASH) is a severe form of non-
alcoholic fatty liver disease (NAFLD, also known as MASLD). Emerging data indicate that …

BACKGROUND The formation of liver fibrosis is mainly caused by the activation of hepatic
stellate cells (HSCs) and the imbalance of extracellular matrix (ECM) production and …

NOD-like receptors (NLRs) are a family of intracellular pattern recognition receptors (PRRs)
that play critical roles in innate immunity against pathogens infection. NLRC5, the largest …

The term “pattern recognition receptor”(PRR) describes a diverse set of receptors that
recognize and differentiate between incoming microbial challenges and damage to self …

NLRC5, a protein belonging to the NOD-like receptor protein family (NLRs), is highly
expressed in immune tissues and cells. NLRC5 plays an important role in the immune …

Salmonella challenge leads to systemic responses that induce the hypozincaemia in mice,
which is considered a vital strategy against Salmonella invasion. However, it is not yet …

Background The beak deformity (crossed beaks) was found in some indigenous chickens of
China, such as Bei**g-You (BJY), Qingyuan Partridge, and Huxu Chickens. Birds with …