Unraveling the obesity of OLETF rats

TH Moran - Physiology & behavior, 2008 - Elsevier
Cholecystokinin (CCK) is a brain gut peptide that plays an important role in satiety. CCK
inhibits food intake by reducing meal size. CCK's satiety actions are mediating through its …

Obesity in the Otsuka Long Evans Tokushima Fatty rat: mechanisms and discoveries

S Bi, TH Moran - Frontiers in nutrition, 2016 - frontiersin.org
Understanding the neural systems underlying the controls of energy balance has been
greatly advanced by identifying the deficits and underlying mechanisms in rodent obesity …

Behavioral effects of environmental enrichment during gestation in WKY and Wistar rats

A Rosenfeld, A Weller - Behavioural brain research, 2012 - Elsevier
Effects of prenatal environmental enrichment (EE) were examined in Wistar Kyoto
(WKY)“depressive-and anxious-like” rats and Wistar rats. During gestation, dams lived in …

Development of obesity in the Otsuka Long-Evans Tokushima fatty rat

M Schroeder, O Zagoory-Sharon… - American Journal …, 2009 - journals.physiology.org
Understanding the early factors affecting obesity development in males and females may
help to prevent obesity and may lead to the discovery of more effective treatments for those …

Post-weaning voluntary exercise exerts long-term moderation of adiposity in males but not in females in an animal model of early-onset obesity

M Schroeder, L Shbiro, V Gelber, A Weller - Hormones and behavior, 2010 - Elsevier
Given the alarming increase in childhood, adolescent and adult obesity there is an
imperative need for understanding the early factors affecting obesity and for treatments that …

Anxiety-like behavior and locomotion in CCK1 knockout rats as a function of strain, sex and early maternal environment

M Schroeder, A Weller - Behavioural brain research, 2010 - Elsevier
CCK is a peptide broadly distributed in the brain that is involved in the regulation of
emotional behaviors through its binding to CCK1 and CCK2 receptors. Research has shown …

Maternal testosterone and reproductive outcome in a rat model of obesity

L Arnon, N Hazut, T Tabachnik, A Weller, L Koren - Theriogenology, 2016 - Elsevier
Global sex differences in obesity rates are persistent, suggesting the involvement of sex
steroids. In addition, adipose tissue is a metabolic site for steroidogenesis. Here, we …

Attenuation of obesity by early-life food restriction in genetically hyperphagic male OLETF rats: peripheral mechanisms

M Schroeder, TH Moran, A Weller - Hormones and behavior, 2010 - Elsevier
The alarming increase in childhood, adolescent and adult obesity has exposed the need for
understanding early factors affecting obesity and for treatments that may help prevent or …

Effects of prepubertal-onset exercise on body weight changes up to middle age in rats

D Shindo, T Matsuura, M Suzuki - Journal of Applied …, 2014 - journals.physiology.org
The present study was conducted to examine whether prepubertal-onset exercise might
help adults maintain long-term body weight (BW) reduction and increased energy …

Preobesity in the infant OLETF rat: the role of suckling

M Schroeder, Y Lavi‐Avnon… - … : The Journal of the …, 2007 - Wiley Online Library
Abstract The Otsuka Long Evans Tokushima Fatty (OLETF) rat model of obesity, which lacks
CCK1 receptors, has been extensively investigated over the last decade. We have recently …