Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis
AS Nagle, S Khare, AB Kumar, F Supek… - Chemical …, 2014 - ACS Publications
Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …
Scorpion venom: detriments and benefits
Scorpion venom may cause severe medical complications and untimely death if injected into
the human body. Neurotoxins are the main components of scorpion venom that are known to …
the human body. Neurotoxins are the main components of scorpion venom that are known to …
Bioactive peptides from scorpion venoms: therapeutic scaffolds and pharmacological tools
KP Muiruri, J Zhong, YAO Bing, LAI Ren… - Chinese Journal of …, 2023 - Elsevier
Evolution and natural selection have endowed animal venoms, including scorpion venoms,
with a wide range of pharmacological properties. Consequently, scorpions, their venoms …
with a wide range of pharmacological properties. Consequently, scorpions, their venoms …
Antimicrobial peptides: On future antiprotozoal and anthelminthic applications
K Nogrado, P Adisakwattana, O Reamtong - Acta Tropica, 2022 - Elsevier
Control and elimination of parasitic diseases are nowadays further complicated by
emergence of drug resistance. Drug resistance is a serious threat as there are not many …
emergence of drug resistance. Drug resistance is a serious threat as there are not many …
Analogs of the scorpion venom peptide stigmurin: structural assessment, toxicity, and increased antimicrobial activity
AMS Parente, A Daniele-Silva, AA Furtado, MA Melo… - Toxins, 2018 - mdpi.com
Scorpion venom is a rich source of biologically active components and various peptides with
high-potential therapeutic use that have been characterized for their antimicrobial and …
high-potential therapeutic use that have been characterized for their antimicrobial and …
Natural occurrence in venomous arthropods of antimicrobial peptides active against protozoan parasites
EF Sabia Junior, LFS Menezes, IFS de Araújo… - Toxins, 2019 - mdpi.com
Arthropoda is a phylum of invertebrates that has undergone remarkable evolutionary
radiation, with a wide range of venomous animals. Arthropod venom is a complex mixture of …
radiation, with a wide range of venomous animals. Arthropod venom is a complex mixture of …
Scorpion venom (Odontobuthus doriae) induces apoptosis by depolarization of mitochondria and reduces S-phase population in human breast cancer cells (MCF-7)
Venom of some species of scorpions induces apoptosis and arrests proliferation in cancer
cells. This is an important property that can be harnessed and can lead to isolation of …
cells. This is an important property that can be harnessed and can lead to isolation of …
Scorpion (Odontobuthus doriae) venom induces apoptosis and inhibits DNA synthesis in human neuroblastoma cells
Scorpion and its organs have been used to cure epilepsy, rheumatism, and male impotency
since medieval times. Scorpion venom which contains different compounds like enzyme and …
since medieval times. Scorpion venom which contains different compounds like enzyme and …
Scorpion (Androctonus crassicauda) venom limits growth of transformed cells (SH-SY5Y and MCF-7) by cytotoxicity and cell cycle arrest
The purpose of study was to examine the cytotoxic and anti-cancer properties along with
addressing the plausible pathway followed by scorpion venom to reduce cell viability in SH …
addressing the plausible pathway followed by scorpion venom to reduce cell viability in SH …
Systematic review of antiprotozoal potential of antimicrobial peptides
Protozoa is a group of microorganisms that cause neglected tropical diseases, such as
malaria, Chagas disease, and Leishmaniasis. Due to the growing demand for new …
malaria, Chagas disease, and Leishmaniasis. Due to the growing demand for new …