Biodegradable microspheres have been widely used in the field of medicine due to their
ability to deliver drug molecules of various properties through multiple pathways and their …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

The osteochondral defect repair has been most extensively studied due to the rising
demand for new therapies to diseases such as osteoarthritis. Tissue engineering has been …

Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Background The regeneration and repair of articular cartilage remains a major challenge for
clinicians and scientists due to the poor intrinsic healing of this tissue. Since cartilage …

Chitosan hydrogels have a wide range of applications in tissue engineering scaffolds,
mainly due to the advantages of their chemical and physical properties. This review focuses …

Reperfusion therapy is widely used to treat acute myocardial infarction. However, its efficacy
is limited by myocardial ischemia-reperfusion injury (MIRI), which occurs paradoxically due …

Post-traumatic osteoarthritis (PTOA) develops secondary to a joint injury and accounts for
12% of all osteoarthritis. These injuries, often of the lower extremity joints, occur due to …

Successful regeneration of cartilage tissue at a clinical scale has been a tremendous
challenge in the past decades. Microcarriers (MCs), usually used for cell and drug delivery …

There are many studies on specific macromolecules and their contributions to tissue repair.
Macromolecules have supporting and protective effects in organisms and can help regrow …