The sleep-immune crosstalk in health and disease

L Besedovsky, T Lange, M Haack - Physiological reviews, 2019 - journals.physiology.org
Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Sleep and inflammation: partners in sickness and in health

MR Irwin - Nature Reviews Immunology, 2019 - nature.com
The discovery of reciprocal connections between the central nervous system, sleep and the
immune system has shown that sleep enhances immune defences and that afferent signals …

[HTML][HTML] Gut microbiome diversity is associated with sleep physiology in humans

RP Smith, C Easson, SM Lyle, R Kapoor, CP Donnelly… - PloS one, 2019 - journals.plos.org
The human gut microbiome can influence health through the brain-gut-microbiome axis.
Growing evidence suggests that the gut microbiome can influence sleep quality. Previous …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

Sleep disturbance, sleep duration, and inflammation: a systematic review and meta-analysis of cohort studies and experimental sleep deprivation

MR Irwin, R Olmstead, JE Carroll - Biological psychiatry, 2016 - Elsevier
Background Sleep disturbance is associated with inflammatory disease risk and all-cause
mortality. Here, we assess global evidence linking sleep disturbance, sleep duration, and …

Inflammation in fear-and anxiety-based disorders: PTSD, GAD, and beyond

V Michopoulos, A Powers, CF Gillespie… - …, 2017 - nature.com
The study of inflammation in fear-and anxiety-based disorders has gained interest as
growing literature indicates that pro-inflammatory markers can directly modulate affective …

Short sleep duration and cardiometabolic risk: from pathophysiology to clinical evidence

E Tobaldini, EM Fiorelli, M Solbiati… - Nature Reviews …, 2019 - nature.com
Short sleep duration has a substantial influence on the overall health of an individual. Short
sleep time can be a consequence of lifestyle habits, environmental factors, or the presence …

Imaging the role of inflammation in mood and anxiety-related disorders

JC Felger - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

Saturation effects of the relationship between physical exercise and systemic immune inflammation index in the short-sleep population: a cross-sectional study

Y You, A Ablitip, Y Chen, H Ding, K Chen, Y Cui… - BMC Public Health, 2024 - Springer
Background Short sleep can lead to an increase in inflammation and regular exercise has
been shown to have a mitigation effect. However, the association between physical exercise …

Sleep health: reciprocal regulation of sleep and innate immunity

MR Irwin, MR Opp - Neuropsychopharmacology, 2017 - nature.com
Sleep disturbances including insomnia independently contribute to risk of inflammatory
disorders and major depressive disorder. This review and overview provides an integrated …