Bacterial persisters: molecular mechanisms and therapeutic development
H Niu, J Gu, Y Zhang - Signal transduction and targeted therapy, 2024 - nature.com
Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
Bacterial stress responses as potential targets in overcoming antibiotic resistance
J Dawan, J Ahn - Microorganisms, 2022 - mdpi.com
Bacteria can be adapted to adverse and detrimental conditions that induce general and
specific responses to DNA damage as well as acid, heat, cold, starvation, oxidative …
specific responses to DNA damage as well as acid, heat, cold, starvation, oxidative …
Fast bacterial growth reduces antibiotic accumulation and efficacy
Phenotypic variations between individual microbial cells play a key role in the resistance of
microbial pathogens to pharmacotherapies. Nevertheless, little is known about cell …
microbial pathogens to pharmacotherapies. Nevertheless, little is known about cell …
Effects and molecular mechanism of flagellar gene flgK on the motility, adhesion/invasion, and desiccation resistance of Cronobacter sakazakii
P Li, W Zong, Z Zhang, W Lv, X Ji, D Zhu, X Du… - Food Research …, 2023 - Elsevier
Abstract Cronobacter sakazakii (C. sakazakii), a food-borne pathogen, can infect neonates,
elderly and immunocompromised populations with a high infection and mortality rate …
elderly and immunocompromised populations with a high infection and mortality rate …
Bacterial proton motive force as an unprecedented target to control antimicrobial resistance
B Yang, Z Tong, J Shi, Z Wang… - Medicinal Research …, 2023 - Wiley Online Library
Novel antibacterial therapies are urgently required to tackle the increasing number of
multidrug‐resistant pathogens. Identification of new antimicrobial targets is critical to avoid …
multidrug‐resistant pathogens. Identification of new antimicrobial targets is critical to avoid …
The effect of disinfectants and antiseptics on co-and cross-selection of resistance to antibiotics in aquatic environments and wastewater treatment plants
D Basiry, N Entezari Heravi, C Uluseker… - Frontiers in …, 2022 - frontiersin.org
The outbreak of the SARS-CoV-2 pandemic led to increased use of disinfectants and
antiseptics (DAs), resulting in higher concentrations of these compounds in wastewaters …
antiseptics (DAs), resulting in higher concentrations of these compounds in wastewaters …
Valnemulin restores colistin sensitivity against multidrug-resistant gram-negative pathogens
C Xu, Y Zhang, L Ma, G Zhang, C Li, C Zhang… - Communications …, 2024 - nature.com
Colistin is one of the last-resort antibiotics in treating infections caused by multidrug-resistant
(MDR) pathogens. Unfortunately, the emergence of colistin-resistant gram-negative strains …
(MDR) pathogens. Unfortunately, the emergence of colistin-resistant gram-negative strains …
Investigation of the impact of widely used pesticides on conjugative transfer of multidrug resistance plasmids
S Zhu, B Yang, F Yu, J Zhang, Z Wang, Y Liu - Journal of Hazardous …, 2024 - Elsevier
Plasmid-mediated conjugative transfer has emerged as a major driver accounting for the
dissemination of antibiotic resistance genes (ARGs). In addition to the use of antimicrobial …
dissemination of antibiotic resistance genes (ARGs). In addition to the use of antimicrobial …
Mechanism of action of isopropoxy benzene guanidine against multidrug-resistant pathogens
J Li, X Zhang, N Han, P Wan, F Zhao, T Xu… - Microbiology …, 2023 - Am Soc Microbiol
The increasing emergence of antibiotic resistance is an urgent threat to global health care;
thus, there is a need for new therapeutics. Guanidine is the preferred functional group for …
thus, there is a need for new therapeutics. Guanidine is the preferred functional group for …
L-glutamine sensitizes Gram-positive-resistant bacteria to gentamicin killing
L Fan, Z Pan, Y Zhong, J Guo, X Liao… - Microbiology …, 2023 - Am Soc Microbiol
Because of the stubborn resistance to antibiotics, treating clinically resistant bacteria is a
tricky business. Although considerable attention has been devoted to preventing and …
tricky business. Although considerable attention has been devoted to preventing and …