The tyrosinase enzyme, which is widely found in microorganisms, animals and plants, has a
significant position in melanogenesis, plays an important role in undesirable browning of …

Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …

Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …

Tyrosinase and its related proteins are responsible for pigmentation disorders, and inhibiting
tyrosinase is an established strategy to treat hyperpigmentation. The carbonyl scaffolds can …

Abstract A series of new 1, 2, 3-triazole linked coumarinopyrazole conjugates 4a-e and 5a-e
have been synthesized via the Copper (I)-catalysed Alkyne-Azide Cycloaddition (CuAAC) …

A new series of antibacterial pyrazolo-triazolo-pyrimidine derivatives 3a-3i were synthesized
in two steps starting from aminopyrazole 1 and characterized by 1 H NMR 13 C NMR and …

Tyrosinase (Polyphenol oxidase), a key enzyme in enzymatic browning, is an attractive
target for develo** new anti-browning agents in the food industry. In this work, twenty …

Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological
properties, which could play a major role in the common mechanisms associated with …

Tyrosinase plays a central role in the biosynthesis pathway of melanin pigment and its
activity has also been linked to Parkinson's and other neurodegenerative diseases. Melanin …

Pyrimidine-fused compounds are of great interest for the discovery of potent bioactive
agents. This study describes the synthesis of novel pyranopyrimidines 3a-f and …