Recurrent pregnancy loss

E Dimitriadis, E Menkhorst, S Saito… - Nature reviews disease …, 2020 - nature.com
Recurrent pregnancy loss is a distressing pregnancy disorder experienced by~ 2.5% of
women trying to conceive. Recurrent pregnancy loss is defined as the failure of two or more …

Interplay between platelets and coagulation

Y Sang, M Roest, B de Laat, PG de Groot, D Huskens - Blood reviews, 2021 - Elsevier
Haemostasis stops bleeding at the site of vascular injury and maintains the integrity of blood
vessels through clot formation. This regulated physiological process consists of complex …

Editor's Choice–European Society for Vascular Surgery (ESVS) 2021 clinical practice guidelines on the management of venous thrombosis

SK Kakkos, M Gohel, N Baekgaard… - European Journal of …, 2021 - ejves.com
2.1. 1. Epidemiology and burden of the disease. The annual incidence of first episode of
symptomatic DVT in the adult population ranges from 50 to 100 per 100 000 population, with …

Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome

V Pengo, G Denas, G Zoppellaro… - Blood, The Journal …, 2018 - ashpublications.org
Rivaroxaban is an effective and safe alternative to warfarin in patients with atrial fibrillation
and venous thromboembolism. We tested the efficacy and safety of rivaroxaban compared …

Pharmacological agents targeting thromboinflammation in COVID-19: review and implications for future research

B Bikdeli, MV Madhavan, A Gupta… - Thrombosis and …, 2020 - thieme-connect.com
Coronavirus disease 2019 (COVID-19), currently a worldwide pandemic, is a viral illness
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The …

American Society of Hematology 2023 guidelines for management of venous thromboembolism: thrombophilia testing

S Middeldorp, R Nieuwlaat… - Blood …, 2023 - ashpublications.org
Background Hereditary and acquired thrombophilia are risk factors for venous
thromboembolism (VTE). Whether testing helps guide management decisions is …

Interferons and proinflammatory cytokines in pregnancy and fetal development

LJ Yockey, A Iwasaki - Immunity, 2018 - cell.com
Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …

[HTML][HTML] Antiphospholipid antibodies in patients with COVID‐19: a relevant observation?

KMJ Devreese, EA Linskens, D Benoit… - Journal of Thrombosis …, 2020 - Elsevier
Background High incidence of thrombosis in COVID‐19 patients indicates a
hypercoagulable state. Hence, exploring the involvement of antiphospholipid antibodies …

Neuropsychiatric lupus: new mechanistic insights and future treatment directions

N Schwartz, AD Stock, C Putterman - Nature Reviews Rheumatology, 2019 - nature.com
Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

Rivaroxaban versus vitamin K antagonist in antiphospholipid syndrome: a randomized noninferiority trial

J Ordi-Ros, L Sáez-Comet… - Annals of internal …, 2019 - acpjournals.org
Background: The potential role of new oral anticoagulants in antiphospholipid antibody
syndrome (APS) remains uncertain. Objective: To determine whether rivaroxaban is …