Human health is intimately connected and tied to the health of our environment and
ecosystem, with only a very small fraction of the risk for chronic diseases explained by …

DNA methylation profiles have been used to develop biomarkers of aging known as
epigenetic clocks, which predict chronological age with remarkable accuracy and show …

As the most phenotypically diverse mammalian species that shares human environments
and access to sophisticated healthcare, domestic dogs have unique potential to inform our …

Simple Summary The intestinal tract affects the brain through metabolites produced by gut-
inhabiting bacteria. In this study, we show that the number of errors the dogs commit in a …

Biological aging is the single most important risk factor for disease, disability, and ultimately
death in geriatric dogs. The effects of aging in companion dogs also impose significant …

Age is a primary risk factor for multiple comorbidities including neurodegenerative diseases.
Pet dogs and humans represent two populations that have experienced a significant …

The companion dog is one of the most phenotypically diverse species. Variability between
breeds extends not only to morphology and aspects of behaviour, but also to longevity …

Over the last decades, canines have experienced a marked increase in their lifespan,
mirroring human populations. Several authors have pointed out the domestic dog as a …

Aging is the single most important cause of disease, disability, and death in companion
animal species. Contrary to the common view of aging as mysterious and inevitable, it is …

Aging is the leading cause of disability, disease, and death in adult dogs. One major
consequence of aging is diminishing physical function. For normal functioning, basic …