Molecular biomarkers in acute myeloid leukemia
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. The
pathophysiology of this disease is just beginning to be understood at the cellular and …
pathophysiology of this disease is just beginning to be understood at the cellular and …
Prediction of individual response to anticancer therapy: historical and future perspectives
FT Unger, I Witte, KA David - Cellular and molecular life sciences, 2015 - Springer
Since the introduction of chemotherapy for cancer treatment in the early 20th century
considerable efforts have been made to maximize drug efficiency and at the same time …
considerable efforts have been made to maximize drug efficiency and at the same time …
From clonal hematopoiesis to myeloid leukemia and what happens in between: Will improved understanding lead to new therapeutic and preventive opportunities?
Clonal hematopoiesis (CH) as defined by the presence of somatic mutations in genes
associated with myeloid neoplasms (MN) is common in healthy elderly individuals and does …
associated with myeloid neoplasms (MN) is common in healthy elderly individuals and does …
Mass spectrometry of peptides and proteins from human blood
It is difficult to convey the accelerating rate and growing importance of mass spectrometry
applications to human blood proteins and peptides. Mass spectrometry can rapidly detect …
applications to human blood proteins and peptides. Mass spectrometry can rapidly detect …
Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness in humans
Our objective in this exploratory study was to identify novel biomarkers of importance for
acute mountain sickness (AMS) using discovery-based proteomic methods. Peripheral …
acute mountain sickness (AMS) using discovery-based proteomic methods. Peripheral …
Proteomics for identifying mechanisms and biomarkers of drug resistance in cancer
XH Li, C Li, ZQ ** molecular changes
Mutations in the genome of a normal cell can affect the function of its many genes and
pathways. These alterations could eventually transform the cell from a normal to a malignant …
pathways. These alterations could eventually transform the cell from a normal to a malignant …
Proteomics approaches for myeloid leukemia drug discovery
Introduction: Global protein expression profiling between healthy vs diseased states helps
identifying differential expression and post-translational modifications of proteins, thereby …
identifying differential expression and post-translational modifications of proteins, thereby …