Acute traumatic spinal cord injury

I Eli, DP Lerner, Z Ghogawala - Neurologic clinics, 2021 - neurologic.theclinics.com
Acute traumatic spinal cord injury (SCI) is typically associated with devastating outcomes.
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …

The neuroanatomical–functional paradox in spinal cord injury

K Fouad, PG Popovich, MA Kopp… - Nature Reviews …, 2021 - nature.com
Although lesion size is widely considered to be the most reliable predictor of outcome after
CNS injury, lesions of comparable size can produce vastly different magnitudes of functional …

SCT: Spinal Cord Toolbox, an open-source software for processing spinal cord MRI data

B De Leener, S Lévy, SM Dupont, VS Fonov, N Stikov… - Neuroimage, 2017 - Elsevier
For the past 25 years, the field of neuroimaging has witnessed the development of several
software packages for processing multi-parametric magnetic resonance imaging (mpMRI) to …

Generic acquisition protocol for quantitative MRI of the spinal cord

J Cohen-Adad, E Alonso-Ortiz, M Abramovic… - Nature protocols, 2021 - nature.com
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Composite pain biomarker signatures for objective assessment and effective treatment

I Tracey, CJ Woolf, NA Andrews - Neuron, 2019 - cell.com
Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

PAM50: Unbiased multimodal template of the brainstem and spinal cord aligned with the ICBM152 space

B De Leener, VS Fonov, DL Collins, V Callot, N Stikov… - Neuroimage, 2018 - Elsevier
Template-based analysis of multi-parametric MRI data of the spinal cord sets the foundation
for standardization and reproducibility, thereby hel** the discovery of new biomarkers of …

MRI in traumatic spinal cord injury: from clinical assessment to neuroimaging biomarkers

P Freund, M Seif, N Weiskopf, K Friston… - The Lancet …, 2019 - thelancet.com
Traumatic spinal cord injury occurs when an external physical impact damages the spinal
cord and leads to permanent neurological dysfunction and disability, and it is associated …

[HTML][HTML] Translating state-of-the-art spinal cord MRI techniques to clinical use: A systematic review of clinical studies utilizing DTI, MT, MWF, MRS, and fMRI

AR Martin, I Aleksanderek, J Cohen-Adad… - NeuroImage: Clinical, 2016 - Elsevier
Background A recent meeting of international imaging experts sponsored by the
International Spinal Research Trust (ISRT) and the Wings for Life Foundation identified 5 …

Spinal cord MRI in multiple sclerosis—diagnostic, prognostic and clinical value

H Kearney, DH Miller, O Ciccarelli - Nature Reviews Neurology, 2015 - nature.com
Multiple sclerosis (MS) is an inflammatory disorder of the CNS that affects both the brain and
the spinal cord. MRI studies in MS focus more often on the brain than on the spinal cord …

Magnetic resonance imaging assessment of degenerative cervical myelopathy: a review of structural changes and measurement techniques

A Nouri, AR Martin, D Mikulis, MG Fehlings - Neurosurgical focus, 2016 - thejns.org
Degenerative cervical myelopathy encompasses a spectrum of age-related structural
changes of the cervical spine that result in static and dynamic injury to the spinal cord and …