Update on food allergy

RL Peters, M Krawiec, JJ Koplin… - Pediatric Allergy and …, 2021 - Wiley Online Library
Food allergy is a major public health issue with growing prevalence in the urbanized world
and significant impact on the lives of allergic patients and their families. Research into the …

[HTML][HTML] Feast for thought: a comprehensive review of food allergy 2021-2023

I Bartha, N Almulhem, AF Santos - Journal of Allergy and Clinical …, 2024 - Elsevier
A review of the latest publications in food allergy over the past couple of years confirmed that
food allergy is a major public health concern, affecting about 8% of children and 10% of …

A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma

J Alladina, NP Smith, T Kooistra, K Slowikowski… - Science …, 2023 - science.org
Asthma is a chronic disease most commonly associated with allergy and type 2
inflammation. However, the mechanisms that link airway inflammation to the structural …

Targeting type 2 immunity and the future of food allergy treatment

MC Berin - Journal of Experimental Medicine, 2023 - rupress.org
IgE-mediated food allergy affects 6–8% of the population in the United States. Type 2
immune responses are central to the pathogenesis of food allergy, but type 2 CD4+ T cell …

Allergen-specific T cells and clinical features of food allergy: lessons from CoFAR immunotherapy cohorts

MC Berin, C Agashe, AW Burks, D Chiang… - Journal of Allergy and …, 2022 - Elsevier
Background Allergen-specific IL-4+ and IL-13+ CD4+ cells (type 2 cells) are essential for
hel** B cells to class-switch to IgE and establishing an allergic milieu in the …

Update on in vitro diagnostic tools and treatments for food allergies

M Brasal-Prieto, L Fernández-Prades, H Dakhaoui… - Nutrients, 2023 - mdpi.com
Food allergy (FA) is an adverse immunological reaction to a specific food that can trigger a
wide range of symptoms from mild to life-threatening. This adverse reaction is caused by …

Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells

B Monian, AA Tu, B Ruiter, DM Morgan… - The Journal of …, 2022 - Am Soc Clin Investig
Food allergy affects an estimated 8% of children in the United States. Oral immunotherapy
(OIT) is a recently approved treatment, with outcomes ranging from sustained tolerance to …

The Immunobiology and Treatment of Food Allergy

S Barshow, J Tirumalasetty, V Sampath… - Annual Review of …, 2024 - annualreviews.org
IgE-mediated food allergy (IgE-FA) occurs due to a breakdown in immune tolerance that
leads to a detrimental type 2 helper T cell (TH2) adaptive immune response. While the …

An update on recent developments and highlights in food allergy

A Locke, L Hung, JEM Upton, L O'Mahony, J Hoang… - Allergy, 2023 - Wiley Online Library
While both the incidence and general awareness of food allergies is increasing, the variety
and clinical availability of therapeutics remain limited. Therefore, investigations into the …

Allergen recognition by specific effector Th2 cells enables IL‐2‐dependent activation of regulatory T‐cell responses in humans

D Lozano‐Ojalvo, SR Tyler, CJ Aranda, J Wang… - Allergy, 2023 - Wiley Online Library
Type 2 allergen‐specific T cells are essential for the induction and maintenance of allergies
to foods, and Tregs specific for these allergens are assumed to be involved in their …