The journey from melanocytes to melanoma

PP Centeno, V Pavet, R Marais - Nature Reviews Cancer, 2023 - nature.com
Over the past decade, melanoma has led the field in new cancer treatments, with impressive
gains in on-treatment survival but more modest improvements in overall survival. Melanoma …

A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Advances in droplet digital polymerase chain reaction on microfluidic chips

D Xu, W Zhang, H Li, N Li, JM Lin - Lab on a Chip, 2023 - pubs.rsc.org
The PCR technique has been known to the general public since the pandemic outbreak of
COVID-19. This technique has progressed through three stages: from simple PCR to real …

Current and emerging applications of droplet digital PCR in oncology: an updated review

S Olmedillas-López, R Olivera-Salazar… - Molecular Diagnosis & …, 2022 - Springer
In the era of personalized medicine and targeted therapies for the management of patients
with cancer, ultrasensitive detection methods for tumor genoty**, such as next-generation …

Recent advances in methods for circulating tumor cell detection

M Vidlarova, A Rehulkova, P Stejskal… - International Journal of …, 2023 - mdpi.com
Circulating tumor cells (CTCs) are released from primary tumors and transported through the
body via blood or lymphatic vessels before settling to form micrometastases under suitable …

Future perspectives of uveal melanoma blood based biomarkers

AB Beasley, FK Chen, TW Isaacs, ES Gray - British Journal of Cancer, 2022 - nature.com
Uveal melanoma (UM) is the most common primary intraocular malignancy affecting adults.
Despite successful local treatment of the primary tumour, metastatic disease develops in up …

Circulating tumor cells (CTCs): a unique model of cancer metastases and non-invasive biomarkers of therapeutic response

J Liu, J Lian, Y Chen, X Zhao, CZ Du, Y Xu, H Hu… - Frontiers in …, 2021 - frontiersin.org
Late-stage cancer metastasis remains incurable in the clinic and is the major cause death in
patients. Circulating tumor cells (CTCs) are thought to be metastatic precursors shed from …

MagPure chip: an immunomagnetic-based microfluidic device for high purification of circulating tumor cells from liquid biopsies

L Descamps, J Garcia, D Barthelemy, E Laurenceau… - Lab on a Chip, 2022 - pubs.rsc.org
The isolation of circulating tumor cells (CTCs) directly from blood, as a liquid biopsy, could
lead to a paradigm shift in cancer clinical care by providing an earlier diagnosis, a more …

Liquid biopsy in melanoma: significance in diagnostics, prediction and treatment monitoring

P Kamińska, K Buszka, M Zabel, M Nowicki… - International Journal of …, 2021 - mdpi.com
Liquid biopsy is a common term referring to circulating tumor cells and other biomarkers,
such as circulating tumor DNA (ctDNA) or extracellular vesicles. Liquid biopsy presents a …

[HTML][HTML] Emerging role of circulating tumor cells in immunotherapy

A Rzhevskiy, A Kapitannikova, P Malinina… - Theranostics, 2021 - ncbi.nlm.nih.gov
Over the last few years, immunotherapy, in particular, immune checkpoint inhibitor therapy,
has revolutionized the treatment of several types of cancer. At the same time, the uptake in …