Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

Bone is a dynamic self-healing organ and a continuous remodeling ensures the restoration
of the bone structure and function over time. However, bone remodeling is not able to repair …

Collagen is the most abundant extracellular matrix protein in food-producing animals.
Gelatin is partially degraded collagen. Collagen peptides refer to the peptides with specific …

Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Successful regeneration of large segmental bone defects remains a major challenge in
clinical orthopedics, thus it is of important significance to fabricate a suitable alternative …

Since the 2010s, the demand for healthcare models has exceeded the prevailing resources
available due to the rapid increase in the aging population in China. However, a significant …

INTRODUCTION The components of bone assemble hierarchically to provide stiffness and
toughness. Deciphering the specific organization and relationship between bone's principal …

Collagen mineralization is a biological process in many skeletal elements in the animal
kingdom. Examples of these collagen‐based skeletons are the siliceous spicules of glass …

Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

Biopolymer nanofibrils exhibit exceptional mechanical properties with a unique combination
of strength and toughness, while also presenting biological functions that interact with the …