[HTML][HTML] Sarcopenic obesity: emerging mechanisms and therapeutic potential

CL Axelrod, WS Dantas, JP Kirwan - Metabolism, 2023 - Elsevier
Sarcopenic obesity, or the loss of muscle mass and function associated with excess
adiposity, is a largely untreatable medical condition associated with diminished quality of life …

Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment

R Cancello, A Brunani, E Brenna, D Soranna… - Reviews in Endocrine …, 2023 - Springer
Phase angle (PhA) is a recently proposed marker of nutritional status in many clinical
conditions. Its use in patients with obesity presents different critical concerns due to the …

[HTML][HTML] Exploring the impact of obesity on skeletal muscle function in older age

PT Morgan, B Smeuninx, L Breen - Frontiers in Nutrition, 2020 - frontiersin.org
Sarcopenia is of important clinical relevance for loss of independence in older adults. The
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …

Intermittent fasting: potential bridge of obesity and diabetes to health?

BY Zang, LX He, L Xue - Nutrients, 2022 - mdpi.com
Obesity has been an escalating worldwide health problem for decades, and it is likely a risk
factor of prediabetes and diabetes. Correlated with obesity, the number of diabetic patients …

Association of low muscle mass and obesity with increased all‐cause and cardiovascular disease mortality in US adults

D Kim, J Lee, R Park, CM Oh… - Journal of Cachexia …, 2024 - Wiley Online Library
Background Sarcopenic obesity, defined as the coexistence of low muscle mass and high
adiposity, is associated with cardiovascular disease (CVD) and mortality. However, to what …

Adiponectin—Consideration for its role in skeletal muscle health

MP Krause, KJ Milne, TJ Hawke - International journal of molecular …, 2019 - mdpi.com
Adiponectin regulates metabolism through blood glucose control and fatty acid oxidation,
partly mediated by downstream effects of adiponectin signaling in skeletal muscle. More …

[HTML][HTML] Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review

O Di Vincenzo, M Marra, AM Sacco, F Pasanisi, L Scalfi - Clinical Nutrition, 2021 - Elsevier
Background & aims Bioimpedance analysis-derived phase angle (PhA), as marker of body
cell mass and cell integrity, might be altered in obesity, a condition which is characterized by …

Obesity-associated poor muscle quality: prevalence and association with age, sex, and body mass index

PL Valenzuela, NA Maffiuletti, G Tringali… - BMC Musculoskeletal …, 2020 - Springer
Background Muscle quality (ie, the expression of muscle function per unit of muscle mass)
has been proposed as a clinically-relevant measure to detect individuals at risk of functional …

5-Heptadecylresorcinol Ameliorates Obesity-Associated Skeletal Muscle Mitochondrial Dysfunction through SIRT3-Mediated Mitophagy

Z Wang, Q Li, H Yang, D Zhang, Y Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Skeletal muscle dysfunction caused by obesity is characterized by the decline in
mitochondrial content and function. 5-Heptadecylresorcinol (AR-C17) is a specific bioactive …

DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling

W Chen, Y Chen, R Wu, G Guo, Y Liu, B Zeng, X Liao… - BMC biology, 2022 - Springer
Background Obesity leads to a decline in the exercise capacity of skeletal muscle, thereby
reducing mobility and promoting obesity-associated health risks. Dietary intervention has …