Antibiotics have transformed medicine, saving millions of lives since they were first used to
treat a bacterial infection. However, antibiotics administered to target a specific pathogen …

Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

Despite enhanced infection prevention efforts, Clostridioides difficile remains the leading
cause of healthcare-associated infections in the United States. Current prevention strategies …

Background Candida auris is an emerging and multidrug-resistant pathogen. Here we report
the epidemiology of a hospital outbreak of C. auris colonization and infection. Methods After …

Background Clostridioides difficile infection is an urgent antibiotic-associated health threat
with few treatment options. Microbiota restoration with faecal microbiota transplantation is an …

Clostridium difficile is a major cause of intestinal infection and diarrhoea in individuals
following antibiotic treatment. Recent studies have begun to elucidate the mechanisms that …

Whole-genome sequences are now available for many microbial species and clades,
however existing whole-genome alignment methods are limited in their ability to perform …

Recombination is an important evolutionary force in bacteria, but it remains challenging to
reconstruct the imports that occurred in the ancestry of a genomic sample. Here we present …

The aim of this paper was to evaluate strategies for periodontal therapy from the perspective
of periodontal disease being a consequence of microbial colonization of the periodontal …