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Nano-formulations for pulmonary delivery: Past, present, and future perspectives
With the development of nanotechnology and confronting the problems of traditional
pharmaceutical formulations in treating lung diseases, inhalable nano-formulations have …
pharmaceutical formulations in treating lung diseases, inhalable nano-formulations have …
Aerosol delivery devices for obstructive lung diseases
RA Pleasants, DR Hess - Respiratory Care, 2018 - liebertpub.com
Drug delivery by inhalation is the principal strategy to treat obstructive lung diseases, which
affect about 15% of the population in the United States. Aerosol delivery devices have …
affect about 15% of the population in the United States. Aerosol delivery devices have …
Optimization of formulation and atomization of lipid nanoparticles for the inhalation of mRNA
H Miao, K Huang, Y Li, R Li, X Zhou, J Shi… - International Journal of …, 2023 - Elsevier
Lipid nanoparticles (LNPs) have demonstrated efficacy and safety for mRNA vaccine
administration by intramuscular injection; however, the pulmonary delivery of mRNA …
administration by intramuscular injection; however, the pulmonary delivery of mRNA …
The function and performance of aqueous aerosol devices for inhalation therapy
TC Carvalho, JT McConville - Journal of Pharmacy and …, 2016 - academic.oup.com
Objectives In this review paper, we explore the interaction between the functioning
mechanism of different nebulizers and the physicochemical properties of the formulations for …
mechanism of different nebulizers and the physicochemical properties of the formulations for …
Protein stability in pulmonary drug delivery via nebulization
Protein inhalation is a delivery route which offers high potential for direct local lung
application of proteins. Liquid formulations are usually available in early stages of …
application of proteins. Liquid formulations are usually available in early stages of …
Inhaled colistin monotherapy for respiratory tract infections in adults without cystic fibrosis: a systematic review and meta-analysis
Background Inhaled colistin is becoming increasingly popular against respiratory tract
infections caused by multidrug resistant (MDR) Gram-negative bacteria because it may …
infections caused by multidrug resistant (MDR) Gram-negative bacteria because it may …
Inhalation therapy in patients receiving mechanical ventilation: an update
A Ari, JB Fink, R Dhand - … of aerosol medicine and pulmonary drug …, 2012 - liebertpub.com
Incremental gains in understanding the influence of various factors on aerosol delivery in
concert with technological advancements over the past 2 decades have fueled an ever …
concert with technological advancements over the past 2 decades have fueled an ever …
[HTML][HTML] How should aerosols be delivered during invasive mechanical ventilation?
R Dhand - Respiratory care, 2017 - liebertpub.com
The delivery of aerosols to mechanically ventilated patients presents unique challenges and
differs from inhaled drug delivery in spontaneously breathing patients in several respects …
differs from inhaled drug delivery in spontaneously breathing patients in several respects …
Devices for improved delivery of nebulized pharmaceutical aerosols to the lungs
Nebulizers have a number of advantages for the delivery of inhaled pharmaceutical
aerosols, including the use of aqueous formulations and the ability to deliver process …
aerosols, including the use of aqueous formulations and the ability to deliver process …
Development and characterization of inhaled nintedanib-loaded PLGA nanoparticles using scalable high-pressure homogenization technique
Presently, non-invasive targeted drug delivery to the lungs represents a routinely
investigated approach to treat challenging disorders such as pulmonary fibrosis. Nintedanib …
investigated approach to treat challenging disorders such as pulmonary fibrosis. Nintedanib …