Smart hydrogels in tissue engineering and regenerative medicine

S Mantha, S Pillai, P Khayambashi, A Upadhyay… - Materials, 2019 - mdpi.com
The field of regenerative medicine has tremendous potential for improved treatment
outcomes and has been stimulated by advances made in bioengineering over the last few …

Hydrogels in regenerative medicine

BV Slaughter, SS Khurshid, OZ Fisher… - Advanced …, 2009 - Wiley Online Library
Hydrogels, due to their unique biocompatibility, flexible methods of synthesis, range of
constituents, and desirable physical characteristics, have been the material of choice for …

Multivascular networks and functional intravascular topologies within biocompatible hydrogels

B Grigoryan, SJ Paulsen, DC Corbett, DW Sazer… - Science, 2019 - science.org
Solid organs transport fluids through distinct vascular networks that are biophysically and
biochemically entangled, creating complex three-dimensional (3D) transport regimes that …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Design and applications of photoresponsive hydrogels

L Li, JM Scheiger, PA Levkin - Advanced Materials, 2019 - Wiley Online Library
Hydrogels are the most relevant biochemical scaffold due to their tunable properties,
inherent biocompatibility, and similarity with tissue and cell environments. Over the past …

Hydrogel scaffolds for tissue engineering: Progress and challenges

IM El-Sherbiny, MH Yacoub - Global Cardiology Science and Practice, 2013 - qscience.com
Designing of biologically active scaffolds with optimal characteristics is one of the key factors
for successful tissue engineering. Recently, hydrogels have received a considerable interest …

Additive manufacturing of tissues and organs

FPW Melchels, MAN Domingos, TJ Klein… - Progress in polymer …, 2012 - Elsevier
Additive manufacturing techniques offer the potential to fabricate organized tissue constructs
to repair or replace damaged or diseased human tissues and organs. Using these …

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

S Khetan, M Guvendiren, WR Legant, DM Cohen… - Nature materials, 2013 - nature.com
Although cell–matrix adhesive interactions are known to regulate stem cell differentiation,
the underlying mechanisms, in particular for direct three-dimensional encapsulation within …

Photodegradable hydrogels for dynamic tuning of physical and chemical properties

AM Kloxin, AM Kasko, CN Salinas, KS Anseth - Science, 2009 - science.org
We report a strategy to create photodegradable poly (ethylene glycol)–based hydrogels
through rapid polymerization of cytocompatible macromers for remote manipulation of gel …

The design of reversible hydrogels to capture extracellular matrix dynamics

AM Rosales, KS Anseth - Nature Reviews Materials, 2016 - nature.com
The extracellular matrix (ECM) is a dynamic environment that constantly provides physical
and chemical cues to embedded cells. Much progress has been made in engineering …