Diabetes and cancer
Diabetes and cancer are two heterogeneous, multifactorial, severe, and chronic diseases.
Because of their frequency, reciprocal influences–even minor influences–may have a major …
Because of their frequency, reciprocal influences–even minor influences–may have a major …
Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease
In mammals, the insulin receptor (IR) gene has acquired an additional exon, exon 11. This
exon may be skipped in a developmental and tissue-specific manner. The IR, therefore …
exon may be skipped in a developmental and tissue-specific manner. The IR, therefore …
[HTML][HTML] Diabetes mellitus, fasting glucose, and risk of cause-specific death
Emerging Risk Factors … - New England Journal of …, 2011 - Mass Medical Soc
Background The extent to which diabetes mellitus or hyperglycemia is related to risk of
death from cancer or other nonvascular conditions is uncertain. Methods We calculated …
death from cancer or other nonvascular conditions is uncertain. Methods We calculated …
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
CJ Currie, CD Poole, EAM Gale - Diabetologia, 2009 - Springer
Aims/hypothesis The risk of develo** a range of solid tumours is increased in type 2
diabetes, and may be influenced by glucose-lowering therapies. We examined the risk of …
diabetes, and may be influenced by glucose-lowering therapies. We examined the risk of …
Dynamic interplay between the collagen scaffold and tumor evolution
The extracellular matrix (ECM) is a key regulator of cell and tissue function. Traditionally, the
ECM has been thought of primarily as a physical scaffold that binds cells and tissues …
ECM has been thought of primarily as a physical scaffold that binds cells and tissues …
Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
R Huxley, A Ansary-Moghaddam… - British journal of …, 2005 - nature.com
Pancreatic cancer is the eighth major form of cancer-related death worldwide, causing 227
000 deaths annually. Type-II diabetes is widely considered to be associated with pancreatic …
000 deaths annually. Type-II diabetes is widely considered to be associated with pancreatic …
Diabetes mellitus and risk of colorectal cancer: a meta-analysis
Background: Diabetes has been associated with an increased risk of colorectal cancer in
most, but not all, studies. Findings have also been inconclusive with regard to sex and …
most, but not all, studies. Findings have also been inconclusive with regard to sex and …
[HTML][HTML] Hyperinsulinemia in obesity, inflammation, and cancer
The relative insufficiency of insulin secretion and/or insulin action causes diabetes.
However, obesity and type 2 diabetes mellitus can be associated with an absolute increase …
However, obesity and type 2 diabetes mellitus can be associated with an absolute increase …
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1–based therapies
BACKGROUND & AIMS: Glucagon-like peptide-1− based therapy is gaining widespread
use for type 2 diabetes, although there are concerns about risks for pancreatitis and …
use for type 2 diabetes, although there are concerns about risks for pancreatitis and …
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
SL Bowker, SR Majumdar, P Veugelers… - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—Numerous studies have identified an increased risk of cancer in type 2
diabetes. We explored the association between antidiabetic therapies and cancer-related …
diabetes. We explored the association between antidiabetic therapies and cancer-related …