[HTML][HTML] Infectious disease in an era of global change
The twenty-first century has witnessed a wave of severe infectious disease outbreaks, not
least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods …
least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods …
Lessons from the host defences of bats, a unique viral reservoir
There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …
SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus)
Widespread human SARS-CoV-2 infections combined with human–wildlife interactions
create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed …
create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed …
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation …
The genome of SARS-CoV-2 encodes two viral proteases (NSP3/papain-like protease and
NSP5/3C-like protease) that are responsible for cleaving viral polyproteins during …
NSP5/3C-like protease) that are responsible for cleaving viral polyproteins during …
SARS-CoV-2 and the human-animal interface: outbreaks on mink farms
M Koopmans - The Lancet. Infectious diseases, 2020 - pmc.ncbi.nlm.nih.gov
On Nov 5, the Ministry of Environment and Food of Denmark announced the culling of all
mink in the country, estimated to total approximately 17 million animals. 1 The circulation of …
mink in the country, estimated to total approximately 17 million animals. 1 The circulation of …
Zoonotic spillover: Understanding basic aspects for better prevention
The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …
Most human infectious diseases (60-75%) are derived from pathogens that originally …
The remarkable evolutionary plasticity of coronaviruses by mutation and recombination: insights for the COVID-19 pandemic and the future evolutionary paths of …
Coronaviruses (CoVs) constitute a large and diverse subfamily of positive-sense single-
stranded RNA viruses. They are found in many mammals and birds and have great …
stranded RNA viruses. They are found in many mammals and birds and have great …
Assessing the risks of SARS-CoV-2 in wildlife
The novel coronavirus SARS-CoV-2 likely emerged from a wildlife source with transmission
to humans followed by rapid geographic spread throughout the globe and severe impacts …
to humans followed by rapid geographic spread throughout the globe and severe impacts …
A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses
The threat of spillovers of coronaviruses associated with the severe acute respiratory
syndrome (SARS) from animals to humans necessitates vaccines that offer broader …
syndrome (SARS) from animals to humans necessitates vaccines that offer broader …
ACE2 receptor usage reveals variation in susceptibility to SARS-CoV and SARS-CoV-2 infection among bat species
Bats are the suggested natural hosts for severe acute respiratory syndrome coronavirus
(SARS-CoV) and the causal agent of the coronavirus disease 2019 (COVID-19) pandemic …
(SARS-CoV) and the causal agent of the coronavirus disease 2019 (COVID-19) pandemic …