Infectious disease in an era of global change

RE Baker, AS Mahmud, IF Miller, M Rajeev… - Nature reviews …, 2022 - nature.com
The twenty-first century has witnessed a wave of severe infectious disease outbreaks, not
least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods …

Lessons from the host defences of bats, a unique viral reservoir

AT Irving, M Ahn, G Goh, DE Anderson, LF Wang - Nature, 2021 - nature.com
There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …

SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus)

JC Chandler, SN Bevins, JW Ellis, TJ Linder… - Proceedings of the …, 2021 - pnas.org
Widespread human SARS-CoV-2 infections combined with human–wildlife interactions
create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed …

Zoonotic spillover: Understanding basic aspects for better prevention

JH Ellwanger, JAB Chies - Genetics and molecular biology, 2021 - SciELO Brasil
The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation …

M Moustaqil, E Ollivier, HP Chiu, S Van Tol… - Emerging microbes & …, 2021 - Taylor & Francis
The genome of SARS-CoV-2 encodes two viral proteases (NSP3/papain-like protease and
NSP5/3C-like protease) that are responsible for cleaving viral polyproteins during …

SARS-CoV-2 and the human-animal interface: outbreaks on mink farms

M Koopmans - The Lancet. Infectious diseases, 2020 - pmc.ncbi.nlm.nih.gov
On Nov 5, the Ministry of Environment and Food of Denmark announced the culling of all
mink in the country, estimated to total approximately 17 million animals. 1 The circulation of …

The remarkable evolutionary plasticity of coronaviruses by mutation and recombination: insights for the COVID-19 pandemic and the future evolutionary paths of …

GD Amoutzias, M Nikolaidis, E Tryfonopoulou… - Viruses, 2022 - mdpi.com
Coronaviruses (CoVs) constitute a large and diverse subfamily of positive-sense single-
stranded RNA viruses. They are found in many mammals and birds and have great …

ACE2 receptor usage reveals variation in susceptibility to SARS-CoV and SARS-CoV-2 infection among bat species

H Yan, H Jiao, Q Liu, Z Zhang, Q **ong… - Nature ecology & …, 2021 - nature.com
Bats are the suggested natural hosts for severe acute respiratory syndrome coronavirus
(SARS-CoV) and the causal agent of the coronavirus disease 2019 (COVID-19) pandemic …

Assessing the risk of human‐to‐wildlife pathogen transmission for conservation and public health

AC Fagre, LE Cohen, EA Eskew, M Farrell… - Ecology …, 2022 - Wiley Online Library
The SARS‐CoV‐2 pandemic has led to increased concern over transmission of pathogens
from humans to animals, and its potential to threaten conservation and public health. To …

Virome in the cloaca of wild and breeding birds revealed a diversity of significant viruses

T Shan, S Yang, H Wang, H Wang, J Zhang, G Gong… - Microbiome, 2022 - Springer
Background Wild birds may harbor and transmit viruses that are potentially pathogenic to
humans, domestic animals, and other wildlife. Results Using the viral metagenomic …