Streptomycetes are the most abundant source of antibiotics. Typically, each species
produces several antibiotics, with the profile being species specific. Streptomyces coelicolor …

While the biological functions of most of the secondary metabolites made by streptomycetes
are not known, it is inconceivable that they do not play an adaptive ecological role. The …

Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Actinomycetes continue to be important sources for the discovery of secondary metabolites
for applications in human medicine, animal health, and crop protection. With the maturation …

Streptomyces is taken as an important resource for producing the most abundant antibiotics
and other bio-active natural products, which have been widely used in pharmaceutical and …

Terpenoids comprise the most chemically and structurally diverse family of natural products.
In contrast to the huge numbers of terpenoids discovered from plants and fungi, only a …

Actinomycetes are remarkable producers of compounds essential for human and veterinary
medicine as well as for agriculture. The genomes of those microorganisms possess several …

The feasibility of using technologies based on site-specific recombination in actinomycetes
was shown several years ago. Despite their huge potential, these technologies mostly have …

Transformation-associated recombination (TAR) in yeast is a rapid and inexpensive method
for cloning and assembly of large DNA fragments, which relies on natural homologous …

Actinomycetes are the main sources of antibiotics. The onset and level of production of each
antibiotic is subject to complex control by multi-level regulators. These regulators exert their …