EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015‏ - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Sex differences in stress response: Classical mechanisms and beyond

GE Hodes, D Bangasser, I Sotiropoulos… - Current …, 2024‏ - benthamdirect.com
Neuropsychiatric disorders, which are associated with stress hormone dysregulation, occur
at different rates in men and women. Moreover, nowadays, preclinical and clinical evidence …

The reversible sex of gonochoristic fish: insights and consequences

JF Baroiller, H d'Cotta - Sexual Development, 2016‏ - karger.com
Fish sex reversal is a means to understand sex determination and differentiation, but it is
also used to control sex in aquaculture. This review discusses sex reversal in gonochoristic …

Neuroactive steroids, neurosteroidogenesis and sex

S Giatti, LM Garcia-Segura, GE Barreto… - Progress in …, 2019‏ - Elsevier
The nervous system is a target and a source of steroids. Neuroactive steroids are steroids
that target neurons and glial cells. They include hormonal steroids originated in the …

The role of estrogen and estrogen receptors on cardiomyocytes: an overview

T Luo, JK Kim - Canadian Journal of Cardiology, 2016‏ - Elsevier
Sex differences in the onset and manifestation of cardiovascular diseases are well known,
yet the mechanism behind this discrepancy remains obscure. Estrogen and its …

Sex differences in behavioral and neurochemical effects of gonadectomy and aromatase inhibition in rats

N Kokras, N Pastromas, D Papasava… - …, 2018‏ - Elsevier
Aromatase inhibitors, which are widely used for the treatment of estrogen-dependent
cancers, have been associated with psychiatric side effects ranging from mania to …

Sex neurosteroids: Hormones made by the brain for the brain

L Fester, GM Rune - Neuroscience Letters, 2021‏ - Elsevier
In general, hippocampal neurons are capable of synthesizing sex steroids de novo from
cholesterol, since the brain is equipped with all the enzymes required for the synthesis of …

Epigenetic impacts of endocrine disruptors in the brain

DM Walker, AC Gore - Frontiers in Neuroendocrinology, 2017‏ - Elsevier
The acquisition of reproductive competence is organized and activated by steroid hormones
acting upon the hypothalamus during critical windows of development. This review …

Molecular, cellular, morphological, physiological and behavioral aspects of gonadotropin-inhibitory hormone

T Ubuka, YL Son, K Tsutsui - General and comparative endocrinology, 2016‏ - Elsevier
Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that was isolated
from the brains of Japanese quail in 2000, which inhibited luteinizing hormone release from …

Sex differences in steroid levels and steroidogenesis in the nervous system: Physiopathological role

S Giatti, S Diviccaro, MM Serafini, D Caruso… - Frontiers in …, 2020‏ - Elsevier
The nervous system, in addition to be a target for steroid hormones, is the source of a variety
of neuroactive steroids, which are synthesized and metabolized by neurons and glial cells …