Phenoty** and genoty** inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod …

M Georgiou, AG Robson, K Fu**ami… - Progress in retinal and …, 2024 - Elsevier
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age
population and in children. The scope of this review is to familiarise clinicians and scientists …

[HTML][HTML] Adaptive optics imaging of the human retina

SA Burns, AE Elsner, KA Sapoznik, RL Warner… - Progress in retinal and …, 2019 - Elsevier
Adaptive Optics (AO) retinal imaging has provided revolutionary tools to scientists and
clinicians for studying retinal structure and function in the living eye. From animal models to …

Progressive cone and cone-rod dystrophies: clinical features, molecular genetics and prospects for therapy

JS Gill, M Georgiou, A Kalitzeos, AT Moore… - British Journal of …, 2019 - bjo.bmj.com
Progressive cone and cone-rod dystrophies are a clinically and genetically heterogeneous
group of inherited retinal diseases characterised by cone photoreceptor degeneration …

Twenty-five years of clinical applications using adaptive optics ophthalmoscopy

JIW Morgan, TYP Chui, K Grieve - Biomedical optics express, 2022 - opg.optica.org
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …

Adaptive optics: principles and applications in ophthalmology

E Akyol, AM Hagag, S Sivaprasad, AJ Lotery - Eye, 2021 - nature.com
This is a comprehensive review of the principles and applications of adaptive optics (AO) in
ophthalmology. It has been combined with flood illumination ophthalmoscopy, scanning …

[HTML][HTML] Adaptive optics imaging in inherited retinal diseases: A sco** review of the clinical literature

AC Britten-Jones, L Thai, JPM Flanagan… - Survey of …, 2024 - Elsevier
Adaptive optics (AO) imaging enables direct, objective assessments of retinal cells.
Applications of AO show great promise in advancing our understanding of the etiology of …

Retinal imaging in inherited retinal diseases

M Georgiou, K Fu**ami… - Annals of eye science, 2020 - pmc.ncbi.nlm.nih.gov
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age
population. The advances in ocular genetics, retinal imaging and molecular biology, have …

Cellular imaging of inherited retinal diseases using adaptive optics

JS Gill, M Moosajee, AM Dubis - Eye, 2019 - nature.com
Adaptive optics (AO) is an insightful tool that has been increasingly applied to existing
imaging systems for viewing the retina at a cellular level. By correcting for individual optical …

Short-term assessment of subfoveal injection of adeno-associated virus-mediated hCHM gene augmentation in choroideremia using adaptive optics ophthalmoscopy

JIW Morgan, YY Jiang, GK Vergilio… - JAMA …, 2022 - jamanetwork.com
Importance Subretinal injection for gene augmentation in retinal degenerations forcefully
detaches the neural retina from the retinal pigment epithelium, potentially damaging …

Molecular Mechanisms Governing Sight Loss in Inherited Cone Disorders

C Brotherton, R Megaw - Genes, 2024 - mdpi.com
Inherited cone disorders (ICDs) are a heterogeneous sub-group of inherited retinal
disorders (IRDs), the leading cause of sight loss in children and working-age adults. ICDs …