The influence of evolutionary history on human health and disease

ML Benton, A Abraham, AL LaBella, P Abbot… - Nature Reviews …, 2021 - nature.com
Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

[HTML][HTML] Cancer cell lines are useful model systems for medical research

P Mirabelli, L Coppola, M Salvatore - Cancers, 2019 - mdpi.com
Cell lines are in vitro model systems that are widely used in different fields of medical
research, especially basic cancer research and drug discovery. Their usefulness is primarily …

Basic principles of biobanking: from biological samples to precision medicine for patients

L Annaratone, G De Palma, G Bonizzi, A Sapino… - Virchows Archiv, 2021 - Springer
The term “biobanking” is often misapplied to any collection of human biological materials
(biospecimens) regardless of requirements related to ethical and legal issues or the …

Variation among DNA banking consent forms: points for clinicians to bank on

SJ Huang, LM Amendola, DL Sternen - Journal of community genetics, 2022 - Springer
Deoxyribonucleic acid (DNA) banking is an important laboratory service that preserves the
option of future genetic testing. DNA bank consent forms are a critical tool to facilitate …

Bioinspired ice-binding materials for tissue and organ cryopreservation

Z Liu, X Zheng, J Wang - Journal of the American Chemical …, 2022 - ACS Publications
Cryopreservation of tissues and organs can bring transformative changes to medicine and
medical science. In the past decades, limited progress has been achieved, although …

Standardizing digital biobanks: integrating imaging, genomic, and clinical data for precision medicine

V Brancato, G Esposito, L Coppola, C Cavaliere… - Journal of Translational …, 2024 - Springer
Advancements in data acquisition and computational methods are generating a large
amount of heterogeneous biomedical data from diagnostic domains such as clinical …

Pharmacogenomics beyond single common genetic variants: the way forward

VM Lauschke, Y Zhou… - Annual Review of …, 2024 - annualreviews.org
Interindividual variability in genes encoding drug-metabolizing enzymes, transporters,
receptors, and human leukocyte antigens has a major impact on a patient's response to …

[HTML][HTML] Revolutionizing cancer research: the impact of artificial intelligence in digital biobanking

C Frascarelli, G Bonizzi, CR Musico, E Mane… - Journal of Personalized …, 2023 - mdpi.com
Background. Biobanks are vital research infrastructures aiming to collect, process, store, and
distribute biological specimens along with associated data in an organized and governed …

A longitudinal SARS-CoV-2 biorepository for COVID-19 survivors with and without post-acute sequelae

SM LaVergne, S Stromberg, BA Baxter, TL Webb… - BMC infectious …, 2021 - Springer
Background SARS-CoV-2 has swept across the globe, causing millions of deaths
worldwide. Though most survive, many experience symptoms of COVID-19 for months after …

Exploring artificial intelligence in anesthesia: a primer on ethics, and clinical applications

M Cascella, MC Tracey, E Petrucci, EG Bignami - Surgeries, 2023 - mdpi.com
The field of anesthesia has always been at the forefront of innovation and technology, and
the integration of Artificial Intelligence (AI) represents the next frontier in anesthesia care …