Cervical cancer

KS Tewari - New England Journal of Medicine, 2025 - Mass Medical Soc
Key Points Cervical Cancer Cervical cancer is preventable through vaccination and
treatment of dysplasia identified on screening (cytologic screening, DNA testing for high-risk …

[HTML][HTML] Cervical cancer: part II the landscape of treatment for persistent, recurrent and metastatic diseases (I)

ST Yang, PH Wang, HH Liu, CW Chang… - Taiwanese Journal of …, 2024 - Elsevier
Abstract The WHO (World Health Organization) conducted an elimination of cervical cancer
program using triple pillar intervention strategy to target 90%-70%-90% of women before the …

Current trends in sensitizing immune checkpoint inhibitors for cancer treatment

J Wei, W Li, P Zhang, F Guo, M Liu - Molecular Cancer, 2024 - Springer
Immune checkpoint inhibitors (ICIs) have dramatically transformed the treatment landscape
for various malignancies, achieving notable clinical outcomes across a wide range of …

A non-comparative, randomized, phase II trial of atezolizumab or atezolizumab plus tiragolumab for programmed death-ligand 1-positive recurrent cervical cancer …

R Salani, M McCormack, YM Kim, S Ghamande… - International Journal of …, 2024 - Elsevier
Objective To evaluate tiragolumab (anti-TIGIT) and atezolizumab (anti-PD-L1) as second-or
third-line therapy for PD-L1-positive persistent/recurrent cervical cancer. Methods In the …

Cervical cancer: a new era

G Caruso, MK Wagar, HC Hsu, J Hoegl… - International Journal of …, 2024 - Elsevier
Cervical cancer is a major global health issue, ranking as the fourth most common cancer in
women worldwide. Depending on stage, histology, and patient factors, the standard …

Treatment advances across the cervical cancer spectrum

AA Francoeur, BJ Monk, KS Tewari - Nature Reviews Clinical Oncology, 2025 - nature.com
Cervical cancer is preventable with screening and vaccination approaches; however,
access to these preventative measures is limited both nationally and globally and thus many …

Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients

L Zhong, L Gan, B Wang, T Wu, F Yao, W Gong… - Cell, 2025 - cell.com
Recently, oncolytic virus (OV) therapy has shown great promise in treating malignancies.
However, intravenous safety and inherent lack of immunity are two significant limitations in …

Advanced, recurrent, and persistent cervical cancer management: in the era of immunotherapy

T Galicia-Carmona, EA Arango-Bravo… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Cervical cancer constitutes a significant health burden for women worldwide despite being
preventable by vaccination and screening. Advanced stages of the disease are associated …

Systemic immune-inflammatory index predict short-term outcome in recurrent/metastatic and locally advanced cervical cancer patients treated with PD-1 inhibitor

Q Chen, B Zhai, J Li, H Wang, Z Liu, R Shi, H Wu… - Scientific Reports, 2024 - nature.com
This study aims to assess the predictive value of certain markers of inflammation in patients
with locally advanced or recurrent/metastatic cervical cancer who are undergoing treatment …

[HTML][HTML] Drugs and Drug Targets for the treatment of HPV-Positive Cervical Cancer

CA Burmeister, SF Khan, S Prince - Tumour Virus Research, 2024 - Elsevier
Cervical cancer is primarily driven by persistent infection with high-risk human
papillomavirus (HPV) strains and remains a significant global health challenge, particularly …