Immunotherapy has made significant strides in cancer treatment, particularly through
immune checkpoint blockade (ICB), which has shown notable clinical benefits across …

Celastrol is a pentacyclic triterpenoid extracted from the traditional Chinese medicine
Tripterygium wilfordii Hook F., which has multiple pharmacological activities. In particular …

Background Ovarian carcinoma (OC) is a prevalent gynecological malignancy associated
with high recurrence rates and mortality, often diagnosed at advanced stages. Despite …

Background Ovarian cancer (OC) is one of the most common and most malignant
gynecological malignancies in gynecology. On the other hand, dysregulation of copper …

Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …

High-grade serous ovarian cancer (HGSOC) is a lethal malignancy characterized by an
immunosuppressive tumor microenvironment containing few tumor infiltrating lymphocytes …

The tumor microenvironment (TME) in ovarian cancer (OC) has much greater complexity
than previously understood. In response to aggressive pro-angiogenic stimulus, blood …

Chemoresistance contributes to the majority of deaths in women with ovarian cancer (OC).
Altered DNA repair and metabolic signaling is implicated in mediating therapeutic …

Epithelial ovarian cancer (EOC) is one of the most aggressive forms of gynaecological
malignancies. Survival rates for women diagnosed with OC remain poor as most patients …

Both anaplastic thyroid cancer (ATC) and papillary thyroid cancer (PTC) originate from
thyroid follicular epithelial cells, but ATC has a significantly worse prognosis and shows …