The endocannabinoid system: a potential target for the treatment of various diseases
H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …
balance in internal environment (temperature, mood, and immune system) and energy input …
Targeting cannabinoid receptors: current status and prospects of natural products
Cannabinoid receptors (CB1 and CB2), as part of the endocannabinoid system, play a
critical role in numerous human physiological and pathological conditions. Thus …
critical role in numerous human physiological and pathological conditions. Thus …
TFOS Lifestyle: Impact of lifestyle challenges on the ocular surface
Many factors in the domains of mental, physical, and social health have been associated
with various ocular surface diseases, with most of the focus centered on aspects of dry eye …
with various ocular surface diseases, with most of the focus centered on aspects of dry eye …
Current aspects of the endocannabinoid system and targeted THC and CBD phytocannabinoids as potential therapeutics for Parkinson's and Alzheimer's diseases: a …
Neurodegeneration leading to Parkinson's disease (PD) and Alzheimer's disease (AD) has
become a major health burden globally. Current treatments mainly target controlling …
become a major health burden globally. Current treatments mainly target controlling …
Cannabidiol effectively reverses mechanical and thermal allodynia, hyperalgesia, and anxious behaviors in a neuropathic pain model: Possible role of CB1 and …
The incidence of chronic pain is high in the general population and it is closely related to
anxiety disorders, which promote negative effects on the quality of life. The cannabinoid …
anxiety disorders, which promote negative effects on the quality of life. The cannabinoid …
[HTML][HTML] Cannabidiol nanoemulsion for eye treatment–Anti-inflammatory, wound healing activity and its bioavailability using in vitro human corneal substitute
O Strnad, J Šuman, T Veverková, A Sukupová… - International Journal of …, 2023 - Elsevier
Cannabidiol (CBD) is the non-psychoactive component of the plant Cannabis sativa (L.) that
has great anti-inflammatory benefits and wound healing effects. However, its high …
has great anti-inflammatory benefits and wound healing effects. However, its high …
Positive Allosteric Modulation of CB1 Cannabinoid Receptor Signaling Enhances Morphine Antinociception and Attenuates Morphine Tolerance Without Enhancing …
Opioid analgesics represent a critical treatment for chronic pain in the analgesic ladder of
the World Health Organization. However, their use can result in a number of unwanted side …
the World Health Organization. However, their use can result in a number of unwanted side …
Neuromolecular and behavioral effects of cannabidiol on depressive-associated behaviors and neuropathic pain conditions in mice
Z Shen, N Bao, J Chen, M Tang, L Yang, Y Yang… - …, 2024 - Elsevier
Background and aims Neuropathic pain (NP) has a high incidence in the general
population, is closely related to anxiety disorders, and has a negative impact on the quality …
population, is closely related to anxiety disorders, and has a negative impact on the quality …
Understanding chronic ocular surface pain: an unmet need for targeted drug therapy
Chronic ocular surface pain (COSP) may be defined as a feeling of pain, perceived as
originating from the ocular surface, that persists for> 3 months. COSP is a complex …
originating from the ocular surface, that persists for> 3 months. COSP is a complex …
Negative allosteric modulation of CB1 cannabinoid receptor signaling suppresses opioid-mediated reward
Blockade of cannabinoid type 1 (CB 1)-receptor signaling decreases the rewarding
properties of many drugs of abuse and has been proposed as an anti-addiction strategy …
properties of many drugs of abuse and has been proposed as an anti-addiction strategy …