Microvalve-based bioprinting–process, bio-inks and applications

WL Ng, JM Lee, WY Yeong, MW Naing - Biomaterials science, 2017 - pubs.rsc.org
Bioprinting is an emerging research field that has attracted tremendous attention for various
applications; it offers a highly automated, advanced manufacturing platform for the …

Stem cell cultivation in bioreactors

CAV Rodrigues, TG Fernandes, MM Diogo… - Biotechnology …, 2011 - Elsevier
Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …

Biofabrication: an overview of the approaches used for printing of living cells

CJ Ferris, KG Gilmore, GG Wallace… - Applied microbiology …, 2013 - Springer
The development of cell printing is vital for establishing biofabrication approaches as
clinically relevant tools. Achieving this requires bio-inks which must not only be easily …

High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research

TG Fernandes, MM Diogo, DS Clark, JS Dordick… - Trends in …, 2009 - cell.com
Cellular microarrays are powerful experimental tools for high-throughput screening of large
numbers of test samples. Miniaturization increases assay throughput while reducing reagent …

Electrochemical immunosensor based on AuNPs/ERGO@ CNT nanocomposites by one-step electrochemical co-reduction for sensitive detection of P-glycoprotein in …

TC Lu, YM Sun, Y Zhong, XH Lin, Y Lei… - Biosensors and …, 2023 - Elsevier
Abstract P-glycoprotein (P-gp), a transmembrane glycoprotein widely expressed on the
surface of various cells, is highly associated with multidrug resistance (MDR) that heralds …

Cell-based assay design for high-content screening of drug candidates

G Nierode, PS Kwon, JS Dordick… - Journal of microbiology …, 2016 - pmc.ncbi.nlm.nih.gov
To reduce attrition in drug development, it is crucial to consider the development and
implementation of translational phenotypic assays as well as decipher diverse molecular …

High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening

SJ Kwon, DW Lee, DA Shah, B Ku, SY Jeon… - Nature …, 2014 - nature.com
Differential expression of various drug-metabolizing enzymes (DMEs) in the human liver
may cause deviations of pharmacokinetic profiles, resulting in interindividual variability of …

High-throughput screening (HTS) of anticancer drug efficacy on a micropillar/microwell chip platform

DW Lee, YS Choi, YJ Seo, MY Lee, SY Jeon… - Analytical …, 2014 - ACS Publications
Contemporary cancer therapy refers to treatment based on genetic abnormalities found in
patient's tumor. However, this approach is faced with numerous challenges, including tumor …

Marine biological macromolecules as matrix material for biosensor fabrication

N Bedi, DK Srivastava, A Srivastava… - Biotechnology and …, 2022 - Wiley Online Library
The ocean covers two‐third of our planet and has great biological heterogeneity. Marine
organisms like algae, vertebrates, invertebrates, and microbes are known to provide many …

Patterned superhydrophobic surfaces to process and characterize biomaterials and 3D cell culture

AI Neto, PA Levkin, JF Mano - Materials Horizons, 2018 - pubs.rsc.org
Microarrays are a technological breakthrough for high-throughput screening of large
numbers of assays. We review the evolution of microarray platforms for 3D cell culture to …