Human Wharton's jelly stem cells have unique transcriptome profiles compared to human embryonic stem cells and other mesenchymal stem cells

CY Fong, LL Chak, A Biswas, JH Tan… - Stem Cell Reviews and …, 2011 - Springer
The human umbilical cord that originates from the embryo is an extra-embryonic membrane
and the Wharton's jelly within it is a rich source of stem cells (hWJSCs). It is not definitely …

Human embryonic stem cells: derivation, culture, and differentiation: a review

T Vazin, WJ Freed - Restorative neurology and neuroscience, 2010 - content.iospress.com
The greatest therapeutic promise of human embryonic stem cells (hESC) is to generate
specialized cells to replace damaged tissue in patients suffering from various degenerative …

New cell lines from mouse epiblast share defining features with human embryonic stem cells

PJ Tesar, JG Chenoweth, FA Brook, TJ Davies… - Nature, 2007 - nature.com
The application of human embryonic stem (ES) cells in medicine and biology has an
inherent reliance on understanding the starting cell population. Human ES cells differ from …

Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

N Olova, DJ Simpson, RE Marioni, T Chandra - Aging cell, 2019 - Wiley Online Library
Induced pluripotent stem cells (IPSCs), with their unlimited regenerative capacity, carry the
promise for tissue replacement to counter age‐related decline. However, attempts to realize …

REST maintains self-renewal and pluripotency of embryonic stem cells

SK Singh, MN Kagalwala, J Parker-Thornburg… - Nature, 2008 - nature.com
The neuronal repressor REST (RE1-silencing transcription factor; also called NRSF) is
expressed at high levels in mouse embryonic stem (ES) cells, but its role in these cells is …

Reviewing and updating the major molecular markers for stem cells

R Calloni, EAA Cordero, JAP Henriques… - Stem cells and …, 2013 - liebertpub.com
Stem cells (SC) are able to self-renew and to differentiate into many types of committed cells,
making SCs interesting for cellular therapy. However, the pool of SCs in vivo and in vitro …

A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas

S Assou, T Le Carrour, S Tondeur, S Ström… - Stem …, 2007 - academic.oup.com
Microarray technology provides a unique opportunity to examine gene expression patterns
in human embryonic stem cells (hESCs). We performed a meta-analysis of 38 original …

Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells

N Kossack, J Meneses, S Shefi, HN Nguyen… - Stem …, 2009 - academic.oup.com
Several reports have documented the derivation of pluripotent cells (multipotent germline
stem cells) from spermatogonial stem cells obtained from the adult mouse testis. These …

Derivation of clinically compliant MSCs from CD105+, CD24− differentiated human ESCs

Q Lian, E Lye, K Suan Yeo, E Khia Way Tan… - Stem …, 2007 - academic.oup.com
Adult tissue-derived mesenchymal stem cells (MSCs) have demonstrated therapeutic
efficacy in treating diseases or repairing damaged tissues through mechanisms thought to …

Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1

AB Choo, HL Tan, SN Ang, WJ Fong, A Chin, J Lo… - Stem …, 2008 - academic.oup.com
Future therapeutic applications of differentiated human embryonic stem cells (hESC) carry a
risk of teratoma formation by contaminating undifferentiated hESC. We generated 10 …