[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease

K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

A synthetic overview of benzoxazines and benzoxazepines as anticancer agents

I Chatterjee, K Ali, G Panda - ChemMedChem, 2023 - Wiley Online Library
Benzoxazines and benzoxazepines are nitrogen and oxygen‐containing six and seven‐
membered benzo‐fused heterocyclic scaffolds, respectively. Benzoxazepines and …

Further exploring rm2 metrics for validation of QSPR models

PK Ojha, I Mitra, RN Das, K Roy - Chemometrics and Intelligent Laboratory …, 2011 - Elsevier
Quantitative structure–property relationship (QSPR) models are widely used for prediction of
properties, activities and/or toxicities of new chemicals. Validation strategies check the …

Zinc‐Catalyzed Asymmetric Formal [4+3] Annulation of Isoxazoles with Enynol Ethers by 6π Electrocyclization: Stereoselective Access to 2H‐Azepines

XQ Zhu, ZS Wang, BS Hou, HW Zhang… - Angewandte Chemie …, 2020 - Wiley Online Library
Abstract 6π electrocyclization has attracted interest in organic synthesis because of its high
stereospecificity and atom economy in the construction of versatile 5–7‐membered cycles …

On the use of the metric rm 2 as an effective tool for validation of QSAR models in computational drug design and predictive toxicology

K Roy, I Mitra - Mini Reviews in Medicinal Chemistry, 2012 - ingentaconnect.com
Validation of quantitative structure-activity relationship (QSAR) models plays a key role for
the selection of robust and predictive models that may be employed for further activity …

Rhodium‐Catalyzed Synthesis of 2,5‐Epoxybenzo[f][1,4]oxazepines by Tandem Reaction of 1‐Sulfonyl‐1,2,3‐triazoles and Salicylaldehydes

Y Shi, X Yu, CY Li - European Journal of Organic Chemistry, 2015 - Wiley Online Library
Abstract Readily available 1‐sulfonyl‐1, 2, 3‐triazoles were converted into α‐imino
carbenes in the presence of catalytic amounts of rhodium (II) salts. The carbenes underwent …

[BOK][B] Toxicity: 77 Must-Know Predictions of Organic Compounds: Including Ionic Liquids

MH Keshavarz - 2023 - books.google.com
Due to the advances of various methods for the prediction of toxicity of organic compounds
and ionic liquids (ILs), it is necessary to review these methods for scientists and students. It …

Design, synthesis and in silico evaluation of benzoxazepino (7, 6-b) quinolines as potential antidiabetic agents

P Thiyagamurthy, C Teja, K Naresh, K Gomathi… - Medicinal Chemistry …, 2020 - Springer
The second-generation XPhos palladium preformed catalyst-based C–N cross-coupling
through Buchwald–Hartwig amination with primary and secondary amines towards …

Unstructured models for suspension cultures of Taxus media cells in a bioreactor under substrate-sufficient conditions

CY Zhang, YS Dong, YL Li, CH Fu, CF Zhao… - Biochemical engineering …, 2013 - Elsevier
For a better understanding of the simulation, optimization, and process control in cell
cultures, good kinetic models are necessary for large scale plant cell culture. In this paper …

Synthesis and characterization of nickel, palladium, platinum and cupper with new oxazipine ring

JH Abdulameer, SK Abbas… - IOP Conference Series …, 2019 - iopscience.iop.org
Via cycloaddition reaction new seven membered Oxazipine ring was prepared by reaction of
Schiff base with phthalic anhydride. Then we use the Oxazipine ring as ligand in this …