Survivin expression and targeting in breast cancer

K Jha, M Shukla, M Pandey - Surgical oncology, 2012 - Elsevier
INTRODUCTION: Survivin a multifunctional protein that controls cell division, inhibition of
apoptosis and promotion of angiogenesis. It is expressed in most human neoplasm, but is …

Metastatic triple-negative breast cancer

EA Rakha, S Chan - Clinical oncology, 2011 - Elsevier
The triple-negative class (oestrogen receptor-negative, progesterone receptor-negative and
human epidermal growth factor receptor 2 [HER2]-negative) comprises about 15% of breast …

The expression and clinical significance of the androgen receptor and E-cadherin in triple-negative breast cancer

D Tang, S Xu, Q Zhang, W Zhao - Medical oncology, 2012 - Springer
Triple-negative breast cancer (TNBC) has a poor prognosis and lacks prognostic indicators.
The androgen receptor (AR) and E-cadherin are involved in the pathogenesis of breast …

Survivin signaling in clinical oncology: a multifaceted dragon

JR Kanwar, SK Kamalapuram… - Medicinal research …, 2013 - Wiley Online Library
Survivin is an inhibitor of apoptosis protein (IAP) family member preferentially expressed in a
myriad of clinical cancers. The complex functional mechanism and regulatory roles of …

YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer

K Yamanaka, M Nakata, N Kaneko… - International …, 2011 - spandidos-publications.com
Metastatic triple negative breast cancer [TNBC, with negative expression of estrogen and
progesterone receptors and no overexpression of HER2/neu (ErbB-2)] remains a major …

Survival according to the site of metastasis in triple-negative breast cancer patients: The Peruvian experience

L Piedra-Delgado, D Chambergo-Michilot, Z Morante… - Plos one, 2024 - journals.plos.org
Background Evidence regarding differences in survival associated with the site of metastasis
in triple-negative breast cancer (TNBC) remains limited. Our aim was to analyze the overall …

Cytokeratin 5/6, c-Met expressions, and PTEN loss prognostic indicators in triple-negative breast cancer

M Inanc, M Ozkan, H Karaca, V Berk, O Bozkurt… - Medical oncology, 2014 - Springer
In subgroups of breast cancer, the shortest disease-free and overall survival was observed
in basaloid and human epidermal growth factor receptor-2 groups. CK5/6 expression is a …

Triple-negative breast cancer: clinical and histological correlations

Z Elsawaf, HP Sinn - Breast Care, 2011 - karger.com
Triple-negative breast cancer (TNBC) is characterized by the lack of estrogen and
progesterone receptors and the lack of HER2 expression or amplification. Much interest has …

Doxorubicin and Trifolium pratense L. (Red clover) extract synergistically inhibits brain and lung metastases in 4T1 tumor‐bearing BALB/c mice

M Akbaribazm, MR Khazaei, F Khazaei… - Food Science & …, 2020 - Wiley Online Library
Trifolium pratense L.(Red clover—T. pratense) commonly consumed as a healthy beverage
has been demonstrated to have various biological activities including antioxidant and …

Intratumoral expression level of epidermal growth factor receptor and cytokeratin 5/6 is significantly associated with nodal and distant metastases in patients with basal …

LM Sutton, JS Han, KH Molberg… - American journal of …, 2010 - academic.oup.com
Triple-negative (TN) breast carcinoma, characterized by estrogen receptor, progesterone
receptor, and HER2 negativity, is a group of aggressive tumors that can be further classified …