Photosensitization reactions of biomolecules: definition, targets and mechanisms

MS Baptista, J Cadet, A Greer… - Photochemistry and …, 2021 - Wiley Online Library
Photosensitization reactions have been demonstrated to be largely responsible for the
deleterious biological effects of UV and visible radiation, as well as for the curative actions of …

Contribution of oxidation reactions to photo‐induced damage to cellular DNA

J Cadet, D Angelov, P Di Mascio… - Photochemistry and …, 2024 - Wiley Online Library
This review article is aimed at providing updated information on the contribution of
immediate and delayed oxidative reactions to the photo‐induced damage to cellular …

[PDF][PDF] The Photochemistry of

J Cadet, P Vigny - H. Morrison, Wiley and Sons, New York, 1990 - static.ibg.edu.tr
Several classes of oxidatively generated DNA damage including oxidized purine and
pyrimidine bases, interstrand base crosslinks and DNA-protein crosslinks have been …

Counterion-dependent mechanisms of DNA origami nanostructure stabilization revealed by atomistic molecular simulation

JAL Roodhuizen, PJTM Hendrikx, PAJ Hilbers… - ACS …, 2019 - ACS Publications
The DNA origami technique has proven to have tremendous potential for therapeutic and
diagnostic applications like drug delivery, but the relatively low concentrations of cations in …

DNA–histone cross-link formation via hole trap** in nucleosome core particles

T Wen, M Kermarrec, E Dumont, N Gillet… - Journal of the …, 2023 - ACS Publications
Radical cations (holes) produced in DNA by ionizing radiation and other oxidants yield DNA–
protein cross-links (DPCs). Detailed studies of DPC formation in chromatin via this process …

Tuning protein frameworks via auxiliary supramolecular interactions

S Engilberge, ML Rennie, E Dumont, PB Crowley - ACS nano, 2019 - ACS Publications
Protein crystals with their precise, periodic array of functional building blocks have potential
applications in biomaterials, sensing, and catalysis. This paper describes how a highly …

Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment

S Lores, M Gámez-Chiachio, M Cascallar… - Biomaterials …, 2023 - pubs.rsc.org
Gene therapy has long been proposed for cancer treatment. However, the use of therapeutic
nucleic acids presents several limitations such as enzymatic degradation, rapid clearance …

Synthesis of Original Cyclic Dinucleotide Analogues Using the Sulfo-click Reaction

R Amador, JJ Vasseur, G Birkuš, E Bignon… - Organic …, 2024 - ACS Publications
The stimulator of interferon genes (STING) protein plays a crucial role in the activation of the
innate immune response. Activation of STING is initiated by cyclic dinucleotides (CDNs) …

Origin of the tight binding mode to ACE2 triggered by multi-point mutations in the omicron variant: A dynamic insight

X Zhao, D **ong, S Luo, L Duan - Physical Chemistry Chemical …, 2022 - pubs.rsc.org
The continuous spread of the newly emerged SARS-CoV-2 Omicron variant (B. 1.1. 529)
has become an important reason for the surge in COVID-19 infections. Its numerous mutated …

Ultrafast conformation-dependent charge transfer in N, N, N′, N′-tetramethyl-1, 3-propanediamine: Effect of flexible carbon skeleton on electron lone pair …

B Abulimiti, J Ma, J Wei, H An, X Wang, J Yang… - … Acta Part A: Molecular …, 2024 - Elsevier
Flexible three-carbon skeleton makes N, N, N′, N′-tetramethyl-1, 3-propanediamine
(TMPDA) an important diamine system to investigate the conformation-dependent electron …