Non‐invasive coronary CT angiography‐derived fractional flow reserve: a benchmark study comparing the diagnostic performance of four different computational …

JM Carson, S Pant, C Roobottom… - … journal for numerical …, 2019 - Wiley Online Library
Non‐invasive coronary computed tomography (CT) angiography‐derived fractional flow
reserve (cFFR) is an emergent approach to determine the functional relevance of obstructive …

Computational instantaneous wave‐free ratio (IFR) for patient‐specific coronary artery stenoses using 1D network models

JM Carson, C Roobottom, R Alcock… - … Journal for Numerical …, 2019 - Wiley Online Library
In this work, we estimate the diagnostic threshold of the instantaneous wave‐free ratio (iFR)
through the use of a one‐dimensional haemodynamic framework. To this end, we first …

Artificial intelligence approaches to predict coronary stenosis severity using non-invasive fractional flow reserve

JM Carson, NK Chakshu, I Sazonov… - Proceedings of the …, 2020 - journals.sagepub.com
Fractional flow reserve is the current reference standard in the assessment of the functional
impact of a stenosis in coronary heart disease. In this study, three models of artificial …

A framework for incorporating 3D hyperelastic vascular wall models in 1D blood flow simulations

A Coccarelli, JM Carson, A Aggarwal, S Pant - … and Modeling in …, 2021 - Springer
We present a novel framework for investigating the role of vascular structure on arterial
haemodynamics in large vessels, with a special focus on the human common carotid artery …

Personalising cardiovascular network models in pregnancy: A two‐tiered parameter estimation approach

J Carson, L Warrander, E Johnstone… - … Journal for Numerical …, 2021 - Wiley Online Library
Uterine artery Doppler waveforms are often studied to determine whether a patient is at risk
of develo** pathologies such as pre‐eclampsia. Many uterine waveform indices have …

A physiologically realistic virtual patient database for the study of arterial haemodynamics

G Jones, J Parr, P Nithiarasu… - International Journal for …, 2021 - Wiley Online Library
This study creates a physiologically realistic virtual patient database (VPD), representing the
human arterial system, for the primary purpose of studying the effects of arterial disease on …

A data-driven model to study utero-ovarian blood flow physiology during pregnancy

J Carson, M Lewis, D Rassi, R Van Loon - Biomechanics and modeling in …, 2019 - Springer
In this paper, we describe a mathematical model of the cardiovascular system in human
pregnancy. An automated, closed-loop 1D–0D modelling framework was developed, and …

[HTML][HTML] A personalised computational model of the impact of COVID-19 on lung function under mechanical ventilation

JM Carson, R Van Loon, H Arora - Computers in Biology and Medicine, 2024 - Elsevier
This work proposes a modelling framework to analyse flow and pressure distributions
throughout the lung of mechanically ventilated COVID-19 patients. The methodology …

[PDF][PDF] AI approaches to predict coronary stenosis severity using non-invasive fractional flow reserve prediction

JM Carson, NK Chakshu, I Sazonov, P Nithiarasu - core.ac.uk
Fractional flow reserve (FFR) is the current reference standard in the assessment of the
functional impact of a stenosis in coronary heart disease. In this study, three models of …

[CITATION][C] Using personalised cardiovascular models to identify new diagnostic predictors for pre-eclampsia

C POPP - 2023