Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
[HTML][HTML] Manufacturing challenges and rational formulation development for AAV viral vectors
A Srivastava, KMG Mallela, N Deorkar… - Journal of pharmaceutical …, 2021 - Elsevier
Adeno-associated virus (AAV) has emerged as a leading platform for gene delivery for
treating various diseases due to its excellent safety profile and efficient transduction to …
treating various diseases due to its excellent safety profile and efficient transduction to …
Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …
[HTML][HTML] How sugars protect proteins in the solid state and during drying (review): Mechanisms of stabilization in relation to stress conditions
MA Mensink, HW Frijlink… - European Journal of …, 2017 - Elsevier
This review aims to provide an overview of current knowledge on stabilization of proteins by
sugars in the solid state in relation to stress conditions commonly encountered during drying …
sugars in the solid state in relation to stress conditions commonly encountered during drying …
Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation
Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest
molecules with a capability to respond to external stimuli that can be used for a multitude of …
molecules with a capability to respond to external stimuli that can be used for a multitude of …
Factors affecting the physical stability (aggregation) of peptide therapeutics
KL Zapadka, FJ Becher… - Interface …, 2017 - royalsocietypublishing.org
The number of biological therapeutic agents in the clinic and development pipeline has
increased dramatically over the last decade and the number will undoubtedly continue to …
increased dramatically over the last decade and the number will undoubtedly continue to …
[HTML][HTML] Vaccine instability in the cold chain: mechanisms, analysis and formulation strategies
OS Kumru, SB Joshi, DE Smith, CR Middaugh, T Prusik… - Biologicals, 2014 - Elsevier
Instability of vaccines often emerges as a key challenge during clinical development (lab to
clinic) as well as commercial distribution (factory to patient). To yield stable, efficacious …
clinic) as well as commercial distribution (factory to patient). To yield stable, efficacious …
Biosynthesized gold nanoparticles maintained nitrogen metabolism, nitric oxide synthesis, ions balance, and stabilizes the defense systems to improve salt stress …
Green synthesis of nanoparticles (NPs) is competent in inducing physiological responses in
plants for combating the abiotic stresses. Considering this, salt stress is one of the most …
plants for combating the abiotic stresses. Considering this, salt stress is one of the most …
The role of Raman spectroscopy in biopharmaceuticals from development to manufacturing
Biopharmaceuticals have revolutionized the field of medicine in the types of active
ingredient molecules and treatable indications. Adoption of Quality by Design and Process …
ingredient molecules and treatable indications. Adoption of Quality by Design and Process …
[HTML][HTML] Raman spectroscopy in pharmaceutical product design
Almost 100 years after the discovery of the Raman scattering phenomenon, related
analytical techniques have emerged as important tools in biomedical sciences. Raman …
analytical techniques have emerged as important tools in biomedical sciences. Raman …