[HTML][HTML] The SLC25 mitochondrial carrier family: structure and mechanism
JJ Ruprecht, ERS Kunji - Trends in biochemical sciences, 2020 - cell.com
Members of the mitochondrial carrier family (SLC25) provide the transport steps for amino
acids, carboxylic acids, fatty acids, cofactors, inorganic ions, and nucleotides across the …
acids, carboxylic acids, fatty acids, cofactors, inorganic ions, and nucleotides across the …
The SLC25 carrier family: important transport proteins in mitochondrial physiology and pathology
Members of the mitochondrial carrier family (SLC25) transport a variety of compounds
across the inner membrane of mitochondria. These transport steps provide building blocks …
across the inner membrane of mitochondria. These transport steps provide building blocks …
Mitochondrial uncouplers induce proton leak by activating AAC and UCP1
Mitochondria generate heat due to H+ leak (IH) across their inner membrane. IH results from
the action of long-chain fatty acids on uncoupling protein 1 (UCP1) in brown fat,,,–and …
the action of long-chain fatty acids on uncoupling protein 1 (UCP1) in brown fat,,,–and …
The molecular mechanism of transport by the mitochondrial ADP/ATP carrier
JJ Ruprecht, MS King, T Zögg, AA Aleksandrova… - Cell, 2019 - cell.com
Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP
synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix …
synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix …
[HTML][HTML] The structural basis of secondary active transport mechanisms
LR Forrest, R Krämer, C Ziegler - Biochimica et Biophysica Acta (BBA) …, 2011 - Elsevier
Secondary active transporters couple the free energy of the electrochemical potential of one
solute to the transmembrane movement of another. As a basic mechanistic explanation for …
solute to the transmembrane movement of another. As a basic mechanistic explanation for …
Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching
Abstract Mitochondrial uncoupling protein 2 (UCP2) is an integral membrane protein in the
mitochondrial anion carrier protein family, the members of which facilitate the transport of …
mitochondrial anion carrier protein family, the members of which facilitate the transport of …
Exploring multidimensional free energy landscapes using time-dependent biases on collective variables
A new implementation of the adaptive biasing force (ABF) method is described. This
implementation supports a wide range of collective variables and can be applied to the …
implementation supports a wide range of collective variables and can be applied to the …
Molecular basis of SARS-CoV-2 infection and rational design of potential antiviral agents: modeling and simulation approaches
The emergence in late 2019 of the coronavirus SARS-CoV-2 has resulted in the
breakthrough of the COVID-19 pandemic that is presently affecting a growing number of …
breakthrough of the COVID-19 pandemic that is presently affecting a growing number of …
Perturbations of native membrane protein structure in alkyl phosphocholine detergents: a critical assessment of NMR and biophysical studies
Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …
Interplay of Mg2+, ADP, and ATP in the cytosol and mitochondria: Unravelling the role of Mg2+ in cell respiration
E Gout, F Rébeillé, R Douce… - Proceedings of the …, 2014 - National Acad Sciences
In animal and plant cells, the ATP/ADP ratio and/or energy charge are generally considered
key parameters regulating metabolism and respiration. The major alternative issue of …
key parameters regulating metabolism and respiration. The major alternative issue of …