Simple Summary Neuroblastoma is one of the most diffuse and the deadliest cancer in
children. While many advances have been made in the last few decades to improve patients' …

Metastasis is the major cause of cancer-related deaths. Neuroblastoma (NB), a childhood
tumor has been molecularly defined at the primary cancer site, however, the bone marrow …

Cell motility is a crucial biological process that plays a critical role in the development of
multicellular organisms and is essential for tissue formation and regeneration. However …

Peripheral neuroblastic tumors (PNTs) represent a spectrum of neural-crest-derived tumors,
including neuroblastoma, ganglioneuroblastoma, and ganglioneuroma. Malignant cells in …

Survival in high-risk pediatric neuroblastoma has remained around 50% for the last 20
years, with immunotherapies and targeted therapies having had minimal impact. Here, we …

Abstract Adult Schwann cells (SCs) possess an inherent plastic potential. This plasticity
allows SCs to acquire repair-specific functions essential for peripheral nerve regeneration …

Simple Summary Glioblastoma multiforme (GB) and neuroblastomas (NBs) are nervous
system cancers that are difficult to diagnosis and treat. Chlorotoxin (CTX), is a peptide …

Simple Summary Bone marrow metastasis frequently occurs in patients with solid cancers
and most often leads to poor outcome. Yet, the composition of bone marrow metastases …

In vitro metastatic models are foreseen to introduce a breakthrough in the field of preclinical
screening of more functional small-molecule pharmaceuticals and biologics. To achieve this …

Background The bone marrow (BM) is the most common site of dissemination in patients
with aggressive, metastatic neuroblastoma (NB). However, the molecular mechanisms …