Nanocarrier-based systems for targeted and site specific therapeutic delivery

J Majumder, O Taratula, T Minko - Advanced drug delivery reviews, 2019 - Elsevier
Systemic drug delivery methods such as oral or parenteral administration of free drugs
possess relatively low treatment efficiency and marked adverse side effects. The use of …

Release of small bioactive molecules from physical gels

J Mayr, C Saldías, DD Díaz - Chemical Society Reviews, 2018 - pubs.rsc.org
Pharmaceutical drugs with low water solubility have always received great attention within
the scientific community. The reduced bioavailability and the need of frequent …

Carbopol emulgel loaded with ebastine for urticaria: development, characterization, in vitro and in vivo evaluation

BA Khan, A Ali, KM Hosny, AA Halwani… - Drug …, 2022 - Taylor & Francis
Urticaria affects all age groups of a population. It is triggered by allergens in foods, insect
bites, medications, and environmental conditions. Urticaria is characterized by itching, a …

Recent updates on supramolecular‐based drug delivery–macrocycles and supramolecular gels

VS Saji - The Chemical Record, 2022 - Wiley Online Library
Supramolecules‐based drug delivery has attracted significant recent research attention as it
could enhance drug solubility, retention time, targeting, and stimuli responsiveness. Among …

Beyond covalent crosslinks: applications of supramolecular gels

T Christoff-Tempesta, AJ Lew, JH Ortony - Gels, 2018 - mdpi.com
Traditionally, gels have been defined by their covalently cross-linked polymer networks.
Supramolecular gels challenge this framework by relying on non-covalent interactions for …

Supramolecular synthon approach in designing molecular gels for advanced therapeutics

P Dastidar, R Roy, R Parveen… - Advanced …, 2019 - Wiley Online Library
Low‐molecular‐weight gelators (LMWGs) are an important class of soft materials that offer
various potential applications including drug delivery. Structural diversities of the reported …

Stability, permeability and cytotoxicity of buccal films in allergy treatment

K Pamlényi, G Regdon Jr, D Nemes, F Fenyvesi… - Pharmaceutics, 2022 - mdpi.com
Oral mucoadhesive systems, such as polymer films, are among innovative pharmaceutical
products. These systems can be applied in swallowing problems and can also be used in …

In situ injection of phenylboronic acid based low molecular weight gels for efficient chemotherapy

W Gao, Y Liang, X Peng, Y Hu, L Zhang, H Wu, B He - Biomaterials, 2016 - Elsevier
Injectable low molecular weight gels (LMWGs) based on the derivatives of phenylboronic
acid were prepared and used as substrates for efficient in situ chemotherapy. The gelators …

Unraveling the structure of meclizine dihydrochloride with MicroED

J Lin, J Unge, T Gonen - Advanced Science, 2024 - Wiley Online Library
Abstract Meclizine (Antivert, Bonine) is a first‐generation H1 antihistamine used in the
treatment of motion sickness and vertigo. Despite its wide medical use for over 70 years, its …

Polysaccharide metallohydrogel obtained from Salecan and trivalent chromium: Synthesis and characterization

T Su, X Qi, G Zuo, X Pan, J Zhang, Z Han… - Carbohydrate polymers, 2018 - Elsevier
Here, a new kind of Salecan derived polysaccharide metallohydrogel was reported.
Successful fabrication of Salecan metallohydrogel was verified by Fourier transform infrared …