Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production …

Following detection of bacteria, macrophages switch their metabolism from oxidative
respiration through the tricarboxylic acid cycle to high-rate aerobic glycolysis. This …

Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …

Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

Mycobacterium tuberculosis (Mtb) survives in macrophages by evading delivery to the
lysosome and promoting the accumulation of lipid bodies, which serve as a bacterial source …

The progression of tuberculosis from a latent, subclinical infection to active disease that
culminates in the transmission of infectious bacilli is determined locally at the level of the …

Lipid droplets (LDs) contribute to key pathways important for the physiology and
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …

Two billion people are latently infected with Mycobacterium tuberculosis (Mtb). Mtb-infected
macrophages are likely to be sequestered inside the hypoxic environments of the …

Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …