Fear is an adaptive emotion that mobilizes defensive resources upon confrontation with
danger. However, fear becomes maladaptive and can give rise to the development of …

Avoidance is typically adaptive given it prevents threat. However, avoidance becomes
maladaptive when it is executed out of proportion of threat (ie, excessive or insufficient …

Fear generalization refers to conditioned fear responses extending to related stimuli and
fear overgeneralization is a key feature of pathological anxiety. Along with perception …

Background A habitual avoidance component may enforce the persistence of maladaptive
avoidance behavior in anxiety disorders. Whether habitual avoidance is acquired more …

Background and objectives Typicality asymmetry in generalization refers to enhanced fear
generalization when trained with typical compared to atypical exemplars. Typical exemplars …

Fear generalization refers to the spread of acquired fear to novel stimuli that resemble the
original fear-related stimulus. Preliminary evidence suggests that excessive fear …

Exposure-based therapy for anxiety disorders involves confrontations with feared but
innocuous stimuli to promote inhibitory safety learning and fear extinction. Little is known …

Deficient safety learning has been implicated in the pathogenesis of anxiety disorders.
Despite increased translational interest, there has been limited research on the basis of …

Fear overgeneralization is widely considered to be a core feature of pathological anxiety,
and the excessive spread of fear can be a great burden on patients. Although perceptual …

Fear generalization undergoes marked changes during adolescence, which may relate to
the high prevalence of anxiety disorders. While intolerance of uncertainty (IU) is a key factor …