[HTML][HTML] Progress of exosomes in the diagnosis and treatment of lung cancer

K Xu, C Zhang, T Du, ANA Gabriel, X Wang, X Li… - Biomedicine & …, 2021 - Elsevier
The incidence and mortality of lung cancer account for first place all over the world. Lung
cancer lacks early diagnostic biomarkers; lung cancer patients are usually diagnosed in …

Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine

Z Fan, C Jiang, Y Wang, K Wang, J Marsh… - Nanoscale …, 2022 - pubs.rsc.org
Extracellular vesicles (EVs), as natural carriers of bioactive cargo, have a unique
micro/nanostructure, bioactive composition, and characteristic morphology, as well as …

[HTML][HTML] Transport of extracellular vesicles across the blood-brain barrier: brain pharmacokinetics and effects of inflammation

WA Banks, P Sharma, KM Bullock, KM Hansen… - International journal of …, 2020 - mdpi.com
Extracellular vesicles can cross the blood–brain barrier (BBB), but little is known about
passage. Here, we used multiple-time regression analysis to examine the ability of 10 …

Tumor-derived exosomes promote angiogenesis via adenosine A2B receptor signaling

N Ludwig, SS Yerneni, JH Azambuja, DG Gillespie… - Angiogenesis, 2020 - Springer
Rationale One hallmark of tumor-derived exosomes (TEX) is the promotion of cancer
progression by stimulating angiogenesis. This study was performed to evaluate the role of …

TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype

N Ludwig, SS Yerneni, JH Azambuja… - Journal of …, 2022 - Wiley Online Library
Transforming growth factor β (TGFβ) is a major component of tumor‐derived small
extracellular vesicles (TEX) in cancer patients. Mechanisms utilized by TGFβ+ TEX to …

[HTML][HTML] Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics

Z Payandeh, B Tangruksa, J Synnergren… - Molecular Aspects of …, 2024 - Elsevier
Modern methods of molecular diagnostics and therapy have revolutionized the field of
medicine in recent years by providing more precise and effective tools for detecting and …

Evaluation of exosome proteins by on‐bead flow cytometry

MN Theodoraki, CS Hong, VS Donnenberg… - Cytometry Part …, 2021 - Wiley Online Library
Exosomes, recently re‐named “small extracellular vesicles” or “sEV,” are emerging as an
intercellular communication system. Quantification of the molecular cargo exosomes carry …

[HTML][HTML] Paracrine mechanisms of endothelial progenitor cells in vascular repair

F Yan, X Liu, H Ding, W Zhang - Acta Histochemica, 2022 - Elsevier
Endothelial progenitor cells (EPCs) play an important role in repairing damaged blood
vessels and promoting neovascularization. However, the specific mechanism of EPCs …

[HTML][HTML] Extracellular vesicles and their roles in the tumor immune microenvironment

A Reale, T Khong, A Spencer - Journal of Clinical Medicine, 2022 - mdpi.com
Tumor cells actively incorporate molecules (eg, proteins, lipids, RNA) into particles named
extracellular vesicles (EVs). Several groups have demonstrated that EVs can be transferred …

Effects of glioblastoma-derived extracellular vesicles on the functions of immune cells

OE Musatova, YP Rubtsov - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Glioblastoma is the most aggressive variant of glioma, the tumor of glial origin which
accounts for 80% of brain tumors. Glioblastoma is characterized by astoundingly poor …