Modern advanced therapies for inflammatory bowel diseases: practical considerations and positioning
DI Fudman, RA McConnell, C Ha, S Singh - Clinical Gastroenterology and …, 2024 - Elsevier
The therapeutic armamentarium for management of inflammatory bowel diseases has
expanded dramatically in the last 5 years, with the introduction of several medications with …
expanded dramatically in the last 5 years, with the introduction of several medications with …
Emerging therapies for ulcerative colitis: updates from recent clinical trials
T AlAmeel, A AlMutairdi… - Clinical and Experimental …, 2023 - Taylor & Francis
Ulcerative colitis (UC) is a chronic and progressive inflammatory disorder that affects the
colon. The advent of advanced therapies such as biologic agents and small molecules has …
colon. The advent of advanced therapies such as biologic agents and small molecules has …
Inflammation-driven colorectal cancer associated with colitis: from pathogenesis to changing therapy
Simple Summary Patients with inflammatory bowel disease (IBD) are at an increased risk of
develo** colorectal cancer (CRC), mainly because of chronic intestinal inflammation …
develo** colorectal cancer (CRC), mainly because of chronic intestinal inflammation …
Immunity in digestive diseases: new drugs for inflammatory bowel disease treatment—insights from Phase II and III trials
S Massironi, F Furfaro, S Bencardino, M Allocca… - Journal of …, 2024 - Springer
Background Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and
ulcerative colitis (UC), continues to challenge treatment paradigms. Advancements in …
ulcerative colitis (UC), continues to challenge treatment paradigms. Advancements in …
[HTML][HTML] Integrating evidence to guide use of biologics and small molecules for inflammatory bowel diseases
Advances in science have led to the development of multiple biologics and small molecules
for the treatment of inflammatory bowel diseases (IBDs). This growth in advanced medical …
for the treatment of inflammatory bowel diseases (IBDs). This growth in advanced medical …
Adverse events with risankizumab in the real world: postmarketing pharmacovigilance assessment of the FDA adverse event reporting system
Y Shu, J Chen, Y Ding, Q Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Background Risankizumab, a humanized IgG1 monoclonal antibody that selectively inhibits
IL-23, is currently approved for the treatment of moderate-to-severe plaque psoriasis and …
IL-23, is currently approved for the treatment of moderate-to-severe plaque psoriasis and …
Risankizumab effectiveness and safety in Crohn's disease: real-world data from a large tertiary center
IL23 is a recognized cytokine involved in the path-ogenesis of inflammatory bowel disease
(IBD). 1 The first IL23-targeting agent that became available for clinical use in IBD was …
(IBD). 1 The first IL23-targeting agent that became available for clinical use in IBD was …
The future of advanced therapies for pediatric Crohn's disease
J Gallagher, JR Rosh, B Sahn - Pediatric Drugs, 2023 - Springer
Pediatric Crohn's disease commonly presents with moderate-to-severe intestinal
inflammation with a greater risk of complications if remission is not achieved. Anti-tumor …
inflammation with a greater risk of complications if remission is not achieved. Anti-tumor …
Advancing therapeutic frontiers: a pipeline of novel drugs for luminal and perianal Crohn's disease management
L Bertin, M Crepaldi, M Zanconato… - Therapeutic …, 2024 - journals.sagepub.com
Crohn's disease (CD) is a chronic, complex inflammatory disorder of the gastrointestinal tract
that presents significant therapeutic challenges. Despite the availability of a wide range of …
that presents significant therapeutic challenges. Despite the availability of a wide range of …
Positioning risankizumab in the treatment algorithm of moderate-to-severe Crohn's disease
F Lusetti, F D'Amico, M Allocca, F Furfaro, A Zilli… - …, 2024 - Taylor & Francis
Risankizumab is a humanized monoclonal antibody that inhibits the p19 subunit of IL-23
cytokine. Recently it has been approved for the treatment of patients with moderate-to …
cytokine. Recently it has been approved for the treatment of patients with moderate-to …