Summary Since 1974, the Glasgow Coma Scale has provided a practical method for
bedside assessment of impairment of conscious level, the clinical hallmark of acute brain …

The decrease in mortality and improved outcome for patients with severe traumatic brain
injury over the past 25 years can be attributed to the approach of" squeezing oxygenated …

✓ There is still controversy over whether or not patients should be hyperventilated after
traumatic brain injury, and a randomized trial has never been conducted. The theoretical …

✓ Early results using cerebral perfusion pressure (CPP) management techniques in persons
with traumatic brain injury indicate that treatment directed at CPP is superior to traditional …

✓ Although experimental and pathological studies suggest an important role for ischemia in
the majority of fatal cases of traumatic brain injury, ischemia has been a rare finding in most …

✓ Experimental traumatic brain injury studies have shown that cerebral hyperglycolysis is a
pathophysiological response to injury-induced ionic and neurochemical cascades. This …

✓ The role of cerebral ischemia in the pathophysiology of traumatic brain injury is unclear.
Cerebral blood flow (CBF) measurements with 133 Xe have thus far revealed ischemia in a …

The extent and timing of posttraumatic cerebral hemodynamic disturbances have significant
implications for the monitoring and treatment of patients with head injury. This prospective …

Assessment of cerebral autoregulation is an important adjunct to measurement of cerebral
blood flow for diagnosis, monitoring or prognosis of cerebrovascular disease. The most …

This article comprehensively reviews the lateral fluid percussion (LFP) model of traumatic
brain injury (TBI) in small animal species with particular emphasis on its validity, clinical …