Impaired insulin signalling and allostatic load in Alzheimer disease
The discovery of insulin in 1921 revolutionized the treatment of diabetes and paved the way
for numerous studies on hormone signalling networks and actions in peripheral tissues and …
for numerous studies on hormone signalling networks and actions in peripheral tissues and …
The impact of disease comorbidities in Alzheimer's disease
JA Santiago, JA Potashkin - Frontiers in aging neuroscience, 2021 - frontiersin.org
A wide range of comorbid diseases is associated with Alzheimer's disease (AD), the most
common neurodegenerative disease worldwide. Evidence from clinical and molecular …
common neurodegenerative disease worldwide. Evidence from clinical and molecular …
Association of efficacy of resistance exercise training with depressive symptoms: meta-analysis and meta-regression analysis of randomized clinical trials
Importance The physical benefits of resistance exercise training (RET) are well documented,
but less is known regarding the association of RET with mental health outcomes. To date, no …
but less is known regarding the association of RET with mental health outcomes. To date, no …
Depression—an underrecognized target for prevention of dementia in Alzheimer's disease
FS Dafsari, F Jessen - Translational psychiatry, 2020 - nature.com
It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be
modifiable by the management of risk factors. While several recent guidelines and …
modifiable by the management of risk factors. While several recent guidelines and …
Trajectories of depressive symptoms before diagnosis of dementia: a 28-year follow-up study
A Singh-Manoux, A Dugravot, A Fournier… - JAMA …, 2017 - jamanetwork.com
Importance Neuropsychiatric symptoms, depressive symptoms in particular, are common in
patients with dementia but whether depressive symptoms in adulthood increases the risk for …
patients with dementia but whether depressive symptoms in adulthood increases the risk for …
A meta-analysis on heart rate variability biofeedback and depressive symptoms
Heart rate variability biofeedback (HRVB) has been used for a number of years to treat
depressive symptoms, a common mental health issue, which is often comorbid with other …
depressive symptoms, a common mental health issue, which is often comorbid with other …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
Sex steroids and the female brain across the lifespan: insights into risk of depression and Alzheimer's disease
Despite widespread sex differences in prevalence and presentation of numerous illnesses
affecting the human brain, there has been little focus on the effect of endocrine ageing. Most …
affecting the human brain, there has been little focus on the effect of endocrine ageing. Most …
Depression and risk of develo** dementia
AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …
Depression has been linked with dementia, and growing evidence implies that the timing of …
Depression in older adults
Depression is less prevalent among older adults than among younger adults, but it can have
serious consequences. More than half of cases represent a first onset in later life. Although …
serious consequences. More than half of cases represent a first onset in later life. Although …