The role of nanotechnology in the treatment of viral infections

L Singh, HG Kruger, GEM Maguire… - Therapeutic …, 2017 - journals.sagepub.com
Infectious diseases are the leading cause of mortality worldwide, with viruses in particular
making global impact on healthcare and socioeconomic development. In addition, the rapid …

Mucoadhesion: A promising approach in drug delivery system

S Mansuri, P Kesharwani, K Jain, RK Tekade… - Reactive and functional …, 2016 - Elsevier
Mucoadhesion, the state in which two materials, amongst which one is biological in nature,
adhere to each other for extended periods of time with the help of interfacial forces, provides …

Temperature-responsive multilayer films based on block copolymer-coated silica nanoparticles for long-term release of favipiravir

L Xu, X Zhang, Z Chu, H Wang, Y Li… - ACS Applied Nano …, 2021 - ACS Publications
Using surface-initiated atom-transfer radical polymerization, temperature-responsive block
polymers were functionalized on the surface of silica nanocapsules (SNCs) by a “grafting …

A mussel-inspired film for adhesion to wet buccal tissue and efficient buccal drug delivery

S Hu, X Pei, L Duan, Z Zhu, Y Liu, J Chen… - Nature …, 2021 - nature.com
Administration of drugs via the buccal route has attracted much attention in recent years.
However, develo** systems with satisfactory adhesion under wet conditions and …

Cyclodextrin complexes: Perspective from drug delivery and formulation

S Jacob, AB Nair - Drug development research, 2018 - Wiley Online Library
Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …

[HTML][HTML] An updated overview of the emerging role of patch and film-based buccal delivery systems

S Jacob, AB Nair, SHS Boddu, B Gorain, N Sreeharsha… - Pharmaceutics, 2021 - mdpi.com
Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …

Acyclovir in the treatment of herpes viruses–a review

K Kłysik, A Pietraszek, A Karewicz… - Current medicinal …, 2020 - ingentaconnect.com
Background: Herpes Simplex (HSV) viruses are widely spread, highly contagious human
pathogens. The statistics indicate that 50-90% of adults worldwide are seropositive for these …

Novel and revisited approaches in nanoparticle systems for buccal drug delivery

AS Macedo, PM Castro, L Roque, NG Thomé… - Journal of Controlled …, 2020 - Elsevier
The buccal route is considered patient friendly due to its non-invasive nature and ease of
administration. Such delivery route has been used as an alternative for the delivery of drugs …

Polyethylene glycol-coated zinc oxide nanoparticle: an efficient nanoweapon to fight against herpes simplex virus type 1

A Tavakoli, A Ataei-Pirkooh, G Mm Sadeghi… - …, 2018 - Taylor & Francis
Aim: We aimed to determine the possible inhibitory effects of zinc oxide nanoparticles (ZnO–
NPs) and polyethylene glycol (PEG)-coated ZnO–NPs (ZnO–PEG–NPs) on herpes simplex …

[HTML][HTML] Nanoemulsion based vehicle for effective ocular delivery of moxifloxacin using experimental design and pharmacokinetic study in rabbits

J Shah, AB Nair, S Jacob, RK Patel, H Shah… - Pharmaceutics, 2019 - mdpi.com
Nanoemulsion is one of the potential drug delivery strategies used in topical ocular therapy.
The purpose of this study was to design and optimize a nanoemulsion-based system to …