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The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
Various forms of fibrosis, comprising tissue thickening and scarring, are involved in 40% of
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to …
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to …
Silk sericin: A versatile material for tissue engineering and drug delivery
Sericin is an inexpensive glycoprotein obtained as a by-product in the silk industry. Its
variable amino acid composition and diverse functional groups confer upon it attractive …
variable amino acid composition and diverse functional groups confer upon it attractive …
[HTML][HTML] Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide
Rationale: Cardiac stem cell-derived exosomes have been demonstrated to promote cardiac
regeneration following myocardial infarction in preclinical studies. Recent studies have used …
regeneration following myocardial infarction in preclinical studies. Recent studies have used …
Exosomes Engineered to Express a Cardiomyocyte Binding Peptide Demonstrate Improved Cardiac Retention in Vivo
Injury to the heart results in cardiomyocyte cell death and can lead to pathological
remodeling of remaining cells, contributing to heart failure. Despite the therapeutic potential …
remodeling of remaining cells, contributing to heart failure. Despite the therapeutic potential …
[HTML][HTML] Recent advances in using liposomes for delivery of nucleic acid-based therapeutics
Nucleic acid therapeutics are rapidly expanding because of recent advancements in
production and purification. This class of therapeutics may change the field of disease …
production and purification. This class of therapeutics may change the field of disease …
Nanoparticles for topical drug delivery: Potential for skin cancer treatment
Nanoparticles offer new opportunities for the treatment of skin diseases. The barrier function
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …
Treatment of neurodegenerative disorders through the blood–brain barrier using nanocarriers
N Poovaiah, Z Davoudi, H Peng, B Schlichtmann… - Nanoscale, 2018 - pubs.rsc.org
Neurodegenerative diseases refer to disorders of the central nervous system (CNS) that are
caused by neuronal degradations, dysfunctions, or death. Alzheimer's disease, Parkinson's …
caused by neuronal degradations, dysfunctions, or death. Alzheimer's disease, Parkinson's …
Recent advances in liposome surface modification for oral drug delivery
Oral delivery via the gastrointestinal (GI) tract is the dominant route for drug administration.
Orally delivered liposomal carriers can enhance drug solubility and protect the encapsulated …
Orally delivered liposomal carriers can enhance drug solubility and protect the encapsulated …
Silk fibroin as a natural polymeric based bio-material for tissue engineering and drug delivery systems-A review
SUD Wani, SP Gautam, ZL Qadrie… - International Journal of …, 2020 - Elsevier
The silk fibroin (SF) prepared by Bombyx mori silkworms is one of the mainly abundant
natural fiber and can be obtained simply and economically. SF as bio-material has superior …
natural fiber and can be obtained simply and economically. SF as bio-material has superior …
Non-genetic engineering of cells for drug delivery and cell-based therapy
Cell-based therapy is a promising modality to address many unmet medical needs. In
addition to genetic engineering, material-based, biochemical, and physical science-based …
addition to genetic engineering, material-based, biochemical, and physical science-based …