Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota

M Gressler, NA Löhr, T Schäfer, S Lawrinowitz… - Natural product …, 2021 - pubs.rsc.org
Covering: up to September 2020 Mushroom-forming fungi of the division Basidiomycota
have traditionally been recognised as prolific producers of structurally diverse and often …

Diverse Metabolites and Pharmacological Effects from the Basidiomycetes Inonotus hispidus

Z Wang, X Feng, C Liu, J Gao, J Qi - Antibiotics, 2022 - mdpi.com
Inonotus hispidus mushroom is a popular edible and medicinal mushroom with a long
history of use. It is well known as a medicinal fungus with various health benefits for its …

Structural insights into three sesquiterpene synthases for the biosynthesis of tricyclic sesquiterpenes and chemical space expansion by structure-based mutagenesis

T Lou, A Li, H Xu, J Pan, B **ng, R Wu… - Journal of the …, 2023 - ACS Publications
The cyclization of farnesyl diphosphate (FPP) into highly strained polycyclic sesquiterpenes
is challenging. We here determined the crystal structures of three sesquiterpene synthases …

[HTML][HTML] Systems biology approaches integrated with artificial intelligence for optimized metabolic engineering

M Helmy, D Smith, K Selvarajoo - Metabolic engineering communications, 2020 - Elsevier
Metabolic engineering aims to maximize the production of bio-economically important
substances (compounds, enzymes, or other proteins) through the optimization of the …

Biosynthesis of fungal terpenoids

P Luo, JH Huang, JM Lv, GQ Wang, D Hu… - Natural Product …, 2024 - pubs.rsc.org
Covering: up to August 2023Terpenoids, which are widely distributed in animals, plants, and
microorganisms, are a large group of natural products with diverse structures and various …

Biosynthesis of sesquiterpenes in basidiomycetes: A review

J Wu, X Yang, Y Duan, P Wang, J Qi, JM Gao, C Liu - Journal of fungi, 2022 - mdpi.com
Sesquiterpenes are common small-molecule natural products with a wide range of
promising applications and are biosynthesized by sesquiterpene synthase (STS) …

Progress in biological activities and biosynthesis of edible fungi terpenoids

HY Chen, JY Lei, SL Li, LQ Guo, JF Lin… - Critical Reviews in …, 2023 - Taylor & Francis
The edible fungi have both edible and medicinal functions, in which terpenoids are one of
the most important active ingredients. Terpenoids possess a wide range of biological …

[HTML][HTML] The recent progress of tricyclic aromadendrene-type sesquiterpenoids: Biological activities and biosynthesis

X Yan, J Lin, Z Liu, SD David, D Liang, S Nie, M Ge… - Biomolecules, 2024 - mdpi.com
The tricyclic-aromadendrene-type sesquiterpenes are widely distributed and exhibit a range
of biological activities, including anti-inflammatory, analgesic, antioxidant, antibacterial …

Natural products from endophytic fungi associated with Rubiaceae species

JS Cruz, CA da Silva, L Hamerski - Journal of Fungi, 2020 - mdpi.com
This review presents the chemical diversity and pharmacological properties of secondary
metabolites produced by endophytic fungi associated with various genera of Rubiaceae …

Genetic engineering of yeast, filamentous fungi and bacteria for terpene production and applications in food industry

Z Liang, H Zhi, Z Fang, P Zhang - Food Research International, 2021 - Elsevier
Terpenes are a major class of natural aromatic compounds in grapes and wines to offer the
characteristic flavor and aroma, serving as important quality traits of wine products …