Raman and Fourier transform infrared imaging for characterization of bone material properties

EA Taylor, E Donnelly - Bone, 2020 - Elsevier
As the application of Raman spectroscopy to study bone has grown over the past decade,
making it a peer technology to FTIR spectroscopy, it has become critical to understand their …

The role of matrix composition in the mechanical behavior of bone

M Unal, A Creecy, JS Nyman - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review While thinning of the cortices or trabeculae weakens bone, age-
related changes in matrix composition also lower fracture resistance. This review …

Compositional assessment of bone by Raman spectroscopy

M Unal, R Ahmed, A Mahadevan-Jansen, JS Nyman - Analyst, 2021 - pubs.rsc.org
Raman spectroscopy (RS) is used to analyze the physiochemical properties of bone
because it is non-destructive and requires minimal sample preparation. With over two …

Bone hydration: How we can evaluate it, what can it tell us, and is it an effective therapeutic target?

RK Surowiec, MR Allen, JM Wallace - Bone reports, 2022 - Elsevier
Water constitutes roughly a quarter of the cortical bone by volume yet can greatly influence
mechanical properties and tissue quality. There is a growing appreciation for how water can …

Assessing matrix quality by Raman spectroscopy helps predict fracture toughness of human cortical bone

M Unal, S Uppuganti, S Timur, A Mahadevan-Jansen… - Scientific reports, 2019 - nature.com
Develo** clinical tools that assess bone matrix quality could improve the assessment of a
person's fracture risk. To determine whether Raman spectroscopy (RS) has such potential …

Fracture toughness: bridging the gap between hip fracture and fracture risk assessment

D Dapaah, DR Martel, F Iranmanesh… - Current Osteoporosis …, 2023 - Springer
Abstract Purpose of Review This review surveys recent literature related to cortical bone
fracture mechanics and its application towards understanding bone fragility and hip …

Bone health in type 1 diabetes

VN Shah, RD Carpenter, VL Ferguson… - Current Opinion in …, 2018 - journals.lww.com
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Bone collagen network integrity and transverse fracture toughness of human cortical bone

TL Willett, DY Dapaah, S Uppuganti, M Granke… - Bone, 2019 - Elsevier
Greater understanding of the determinants of skeletal fragility is highly sought due to the
great burden that bone affecting diseases and fractures have on economies, societies and …

Raman spectroscopic determination of bone matrix quantity and quality augments prediction of human cortical bone mechanical properties

M Unal - Journal of Biomechanics, 2021 - Elsevier
Being independent contributors to bone mechanical resistance at the apparent level, quality
and quantity of bone primary constituents are essential factors in better fracture risk …

Spatially offset Raman spectroscopy for in vivo bone strength prediction

C Shu, K Chen, M Lynch, JR Maher… - Biomedical optics …, 2018 - opg.optica.org
Bone strength is a worldwide health concern. Although multiple techniques have been
developed to evaluate bone quality, there are still gaps to be filled. Here we report a non …