Human antimicrobial peptides in ocular surface defense

I Mohammed, DG Said, HS Dua - Progress in retinal and eye research, 2017 - Elsevier
Sight depends on the passage of light through the transparent cornea and being focused on
the fovea. Its exposed position renders it vulnerable to microbial infection. The cornea has …

Insights into chromatin structure and dynamics in plants

S Rosa, P Shaw - Biology, 2013 - mdpi.com
The packaging of chromatin into the nucleus of a eukaryotic cell requires an extraordinary
degree of compaction and physical organization. In recent years, it has been shown that this …

12-year analysis of incidence, microbiological profiles and in vitro antimicrobial susceptibility of infectious keratitis: the Nottingham Infectious Keratitis Study

DSJ Ting, CS Ho, J Cairns, A Elsahn… - British Journal of …, 2021 - bjo.bmj.com
Background/aims To examine the incidence, causative microorganisms and in vitro
antimicrobial susceptibility and resistance profiles of infectious keratitis (IK) in Nottingham …

Risk factors, clinical outcomes, and prognostic factors of bacterial keratitis: the Nottingham Infectious Keratitis Study

DSJ Ting, J Cairns, BP Gopal, CS Ho, L Krstic… - Frontiers in …, 2021 - frontiersin.org
Background/Aim: To examine the risk factors, clinical characteristics, outcomes, and
prognostic factors of bacterial keratitis (BK) in Nottingham, UK. Methods: This was a …

Evolving risk factors and antibiotic sensitivity patterns for microbial keratitis at a large county hospital

H **, WT Parker, NW Law, CL Clarke… - British Journal of …, 2017 - bjo.bmj.com
Purpose: To identify the risk factors, causative organisms, antimicrobial susceptibility and
outcomes of microbial keratitis in a large county hospital in Houston, Texas. Design: Case …

Broad spectrum antimicrobial activity of melimine covalently bound to contact lenses

D Dutta, N Cole, N Kumar… - … ophthalmology & visual …, 2013 - iovs.arvojournals.org
Purpose.: To develop a stable antimicrobial contact lens, which is effective against the
International Organization for Standardization (ISO) panel microorganisms, Acanthamoeba …

PM10 and Pseudomonas aeruginosa: effects on corneal epithelium

M Somayajulu, SA McClellan, F Muhammed… - Frontiers in Cellular …, 2023 - frontiersin.org
Purpose In vivo data indicate that mouse corneas exposed to PM10 showed early
perforation and thinning after infection with Pseudomonas aeruginosa. To understand the …

Association between season, temperature and causative organism in microbial keratitis in the UK

A Walkden, C Fullwood, SZ Tan, L Au, M Armstrong… - Cornea, 2018 - journals.lww.com
Purpose: Microbial keratitis (MK) is a major cause of corneal blindness worldwide.
Variations in season and temperature can affect MK incidence due to specific causative …

Cathelicidin-Derived Synthetic Peptide Improves Therapeutic Potential of Vancomycin Against Pseudomonas aeruginosa

I Mohammed, DG Said, M Nubile… - Frontiers in …, 2019 - frontiersin.org
Pseudomonas aeruginosa (PA) is the leading cause of corneal blindness worldwide. A
constant increase in multi-drug resistant PA strains have heightened the challenge of …

16S ribosomal RNA PCR versus conventional diagnostic culture in the investigation of suspected bacterial keratitis

TF Somerville, CE Corless, H Sueke… - … vision science & …, 2020 - tvst.arvojournals.org
Purpose: The purpose of this study was to compare conventional diagnostic culture (CDC) to
16S ribosomal RNA polymerase chain reaction (PCR) analysis for diagnosing bacterial …